N-(4-chlorophenyl)-2,7-dimethyl-5-oxo-5H-chromeno[2,3-b]pyridine-3-carboxamide CAS 338751-37-4
| CAS No. | 338751-37-4 |
| Molecular Formula | C21H15ClN2O3 |
| Molecular Weight | 378.81 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
N-(4-chlorophenyl)-2,7-dimethyl-5-oxo-5H-chromeno[2,3-b]pyridine-3-carboxamide (CAS 338751-37-4), molecular formula C21H15ClN2O3 and molecular weight 378.81 g/mol, is a CATO reference standard with documented purity and traceability.
Structurally, N-(4-chlorophenyl)-2,7-dimethyl-5-oxo-5H-chromeno[2,3-b]pyridine-3-carboxamide (C21H15ClN2O3) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 15.0, corresponding to approximately 15 ring(s) or double-bond equivalent(s). With a molecular weight of 378.81 g/mol, it falls into the moderately-high-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
CATO manufactures N-(4-chlorophenyl)-2,7-dimethyl-5-oxo-5H-chromeno[2,3-b]pyridine-3-carboxamide under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C21H15ClN2O3 |
| Molecular Weight | 378.81 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
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Recommended Standards
- N-(4-chlorobenzyl)-2-methyl-5-oxo-5H-chromeno[2,3-b]pyridine-3-carboxamide (CAS 338417-61-1)
- N-benzyl-7-chloro-2-methyl-5-oxo-5H-chromeno[2,3-b]pyridine-3-carboxamide (CAS 338778-91-9)
- MF 63 (CAS 892549-43-8)
- Avanafil Impurity 52 (CAS CATO-C4X-111852)
- n-Tetradecyl-1,1-d2 Alcohol (CAS 169398-02-1)
- Ethyl 2,4-dihydroxy-5-nitrobenzoate (CAS 13722-95-7)
- tert-butyl (2R)-1-(2-hydroxyethyl)pyrrolidine-2-carboxylate (CAS 1786802-26-3)
- tert-Butyl 2-(5-bromopyridin-2-yl)-2-cyanoacetate (CAS 1279820-53-9)
- 3-[(2S)-4-cyclopropyl-2-[(2,4-dichlorophenyl)methoxy]-1,1,1-trifluorobut-3-yn-2-yl]-5-ethyl-6-methyl-1H-pyridin-2-one 3-[(2S)-4-cyclopropyl-2-[(2,4-dichlorophenyl)methoxy]-1,1,1-tris(fluoranyl)but-3-yn-2-yl]-5-ethyl-6-methyl-1H-pyridin-2-one 3377-71-7 A821942 (CAS 3377-71-7)
- 4-Iodo-1-tosyl-1H-pyrazole (CAS 116228-40-1)
- 1-(3-Aminopiperidin-1-yl)propan-1-one (CAS 1248172-39-5)
- (3-Bromo-5-formyl-2-methoxyphenyl)boronic acid (CAS 1072951-80-4)
- (E)-2-(2-Methoxystyryl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS 149777-81-1)
- Semaglutide Impurity 15 (CAS CATO-C4X-222615)
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