3-((4-Fluorobenzyl)oxy)thiophene-2-carbohydrazide CAS 338751-50-1
| CAS No. | 338751-50-1 |
| Molecular Formula | C12H11FN2O2S |
| Molecular Weight | 266.29 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
3-((4-Fluorobenzyl)oxy)thiophene-2-carbohydrazide (CAS 338751-50-1) is a high-purity analytical reference standard with the molecular formula C12H11FN2O2S and a molecular weight of 266.29 g/mol.
The molecular framework of 3-((4-Fluorobenzyl)oxy)thiophene-2-carbohydrazide (C12H11FN2O2S) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C12H11FN2O2S |
| Molecular Weight | 266.29 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Fluorobenzyl Standards
- Methyl 2-((4-fluorobenzyl)amino)thiazole-4-carboxylate (CAS 1512655-05-8)
- Methyl 4-((4-fluorobenzyl)oxy)thiophene-2-carboxylate (CAS 1707372-23-3)
- Methyl 4-((3-fluorobenzyl)oxy)thiophene-2-carboxylate (CAS 1779124-53-6)
- 5-{[(2-Fluorobenzyl)thio]methyl}-2-furoic acid (CAS 899710-20-4)
- Methyl 3-((4-fluorobenzyl)oxy)thiophene-2-carboxylate (CAS 338417-95-1)
- N-((4-(3-fluorobenzyl)morpholin-2-yl)methyl)acetamide (CAS 112913-92-5)
- N-[[4-(4-Fluorobenzyl)-2-morpholinyl]methyl]acetamide (CAS 112913-94-7)
- 2-(1-(3-Fluorobenzyl)-3-oxopiperazin-2-yl)acetic acid (CAS 1033399-99-3)
Recommended Standards
- 2-Phenyl-pyrazolo[1,5-a]pyridine-3-carboxylic acid ethyl ester (CAS 51065-76-0)
- 3-(1H-indol-3-yl)-3-(pyridin-3-yl)propanoic acid (CAS 881040-99-9)
- 2-Phenyl-7,8,9,10-tetrahydro-4H-[1,3]oxazino[3,2-b]indazol-4-one (CAS 919533-25-8)
- 3-(1H-indol-3-yl)-3-(pyridin-4-yl)propanoic acid (CAS 797779-89-6)
- Ethyl 4-amino-5-bromopyrrolo[2,1-f][1,2,4]triazine-7-carboxylate (CAS 2091742-74-2)
- 1-cyclopropylpiperazine-2-carboxamide (CAS 1697661-89-4)
- 4-Amino-5-(difluoromethyl)-6-hydroxypyridine-2-sulfonamide (CAS 1805138-76-4)
- 1-Chloro-5-(methylsulfonyl)pentane (CAS 128147-29-5)
- 8-Bromoquinolin-2-amine (CAS 1092304-85-2)
- (E)-3-(2-chloro-phenyl)-prop-2-en-1-ol (CAS 1504-71-8)
- tert-butyl N-[2-(3-methoxy-1,2,4-oxadiazol-5-yl)ethyl]carbamate (CAS 2839902-45-1)
- 2-Fluoro-5-(4-fluoro-2-methylphenyl)benzoic acid (CAS 1178482-85-3)
- Allylescaline (CAS 39201-75-7)
- Semaglutide Impurity 160 (x TFA Salt) (CAS CATO-C4X-2226160)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com