2'-(4-Chlorophenyl)spiro[chromane-3,5'-[1,3]dioxan]-4-one CAS 338755-68-3
| CAS No. | 338755-68-3 |
| Molecular Formula | C18H15ClO4 |
| Molecular Weight | 330.76 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO supplies 2'-(4-Chlorophenyl)spiro[chromane-3,5'-[1,3]dioxan]-4-one (CAS 338755-68-3), a certified reference material (molecular formula C18H15ClO4, MW 330.76 g/mol) for analytical method development and quality control.
The molecular framework of 2'-(4-Chlorophenyl)spiro[chromane-3,5'-[1,3]dioxan]-4-one (C18H15ClO4) is characterized by a flavonoid core, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C18H15ClO4 |
| Molecular Weight | 330.76 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
Related Chlorophenyl Standards
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Recommended Standards
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- 3,8-Difluoro-6-methoxyquinoline (CAS 851973-18-7)
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- 3-(2-Chlorophenyl)dihydro-2,5-furandione (CAS 66041-30-3)
- 1-Phenylpentadecane-d36 (CAS 352431-31-3)
- 3-Borono-5-bromo-2-fluorobenzoic acid (CAS 957120-63-7)
- N-(6-Amino-1-butyl-3-(2-fluorobenzyl)-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)-2-(4-aminophenyl)acetamide (CAS 693217-34-4)
- Ethyl 1-{6-methyl-4-oxo-4H,5H-pyrazolo[1,5-a]pyrazine-2-carbonyl}piperidine-4-carboxylate (CAS 1788673-56-2)
- (4-bromo-5-iodo-2-naphthyl) 2,2-dimethylpropanoate (CAS 2757096-97-0)
- 2-(3,5-Bis(1-hydroxyethyl)-1H-1,2,4-triazol-1-yl)-1-phenylethan-1-one (CAS 302932-39-4)
- (Leu31,Pro34)-Peptide YY (human) trifluoroacetate salt (CAS 179986-95-9)
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