(E)-5-(2-(5-(2,4-dichlorophenyl)furan-2-yl)vinyl)-3-methyl-4-nitroisoxazole CAS 338756-56-2
| CAS No. | 338756-56-2 |
| Molecular Formula | C16H10Cl2N2O4 |
| Molecular Weight | 365.17 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of (E)-5-(2-(5-(2,4-dichlorophenyl)furan-2-yl)vinyl)-3-methyl-4-nitroisoxazole is closely related to a flavonoid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies (E)-5-(2-(5-(2,4-dichlorophenyl)furan-2-yl)vinyl)-3-methyl-4-nitroisoxazole (CAS 338756-56-2), a certified reference material (molecular formula C16H10Cl2N2O4, MW 365.17 g/mol) for analytical method development and quality control.
Owing to a flavonoid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution, (E)-5-(2-(5-(2,4-dichlorophenyl)furan-2-yl)vinyl)-3-methyl-4-nitroisoxazole is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 365.17 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C16H10Cl2N2O4 |
| Molecular Weight | 365.17 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related E Standards
- 3-(3-(2,3-Dichlorophenyl)-2,4-dioxoimidazolidin-1-yl)benzoic acid (CAS 651748-65-1)
- 3-[(E)-2-[(2,4-Dichlorophenyl)amino]-1-nitroethenyl]-1,3-dihydro-2-benzofuran-1-one (CAS 339023-54-0)
- 3-[(E)-2-[(3,5-Dichlorophenyl)amino]-1-nitroethenyl]-1,3-dihydro-2-benzofuran-1-one (CAS 320420-36-8)
- 1-(2,4-Dichlorophenyl)-N-(4-fluorophenyl)-5-methyl-1H-1,2,4-triazole-3-carboxamide (CAS 338398-15-5)
- 1-(2,5-dichlorophenyl)-N-(4-fluorophenyl)-5-methyl-1H-1,2,4-triazole-3-carboxamide (CAS 338398-37-1)
- 1-(3,5-Dichlorophenyl)-N-(4-fluorophenyl)-5-methyl-1H-1,2,4-triazole-3-carboxamide (CAS 338408-23-4)
- Methyl 5-(3,4-dichlorophenyl)-1-(4-fluorophenyl)-1H-pyrazole-3-carboxylate (CAS 318256-22-3)
- N-(2,4-Dichlorophenyl)-1-(4-fluorophenyl)-5-methyl-1H-1,2,4-triazole-3-carboxamide (CAS 338398-12-2)
Recommended Standards
- (3-(4-Bromophenyl)-1-(2,4-difluorophenyl)-1H-pyrazol-4-yl)methanol (CAS 618383-24-7)
- 1-Benzyl-7-iodo-3,4-dihydropyrido[2,3-b]pyrazin-2(1H)-one (CAS 957193-71-4)
- Chloramphenicol 3-Acetate (CAS 10318-16-8)
- 2-Amino-4-(2,6-dichlorophenyl)-6-(hydroxymethyl)-8-oxo-4H,8H-pyrano[3,2-b]pyran-3-carbonitrile (CAS 664999-54-6)
- (S)-2-(1-Amino-3-hydroxypropyl)-5-(trifluoromethyl)benzonitrile (CAS 1336757-01-7)
- 1-Oxoisoindoline-5-carboxamide (CAS 1823367-10-7)
- Laniquidar (CAS 197509-46-9)
- 4-(Methylsulfonyl)benzyl Alcohol (CAS 22821-77-8)
- 4-(4-Chlorophenyl)-3-phenylisoxazolo[4,5-c]quinoline (CAS 253433-32-8)
- 2-(Cyclopropyl((1-methylpiperidin-4-yl)methyl)amino)ethanol (CAS 1353976-61-0)
- Canagliflozin Impurity 5 (CAS CATO-C4X-11235)
- (2R,3S,5R)-5-(2-Amino-6-oxo-3,6-dihydro-9H-purin-9-yl)-2-(hydroxymethyl)tetrahydrofuran-3-yl acetate (CAS 51549-58-7)
- [4-(Carboxymethyl)-3,5-dimethyl-1H-1,2,4-triazol-4-ium-1-yl]acetate (CAS 1452574-96-7)
- Tirzepatide Impurity 11 TFA salt (CAS CATO-C4X-324011)
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