2-(4-Chlorophenyl)-4-(4-methyl-5-((3-(trifluoromethyl)benzyl)thio)-4H-1,2,4-triazol-3-yl)thiazole CAS 338760-88-6
| CAS No. | 338760-88-6 |
| Molecular Formula | C20H14ClF3N4S2 |
| Molecular Weight | 466.93 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 2-(4-Chlorophenyl)-4-(4-methyl-5-((3-(trifluoromethyl)benzyl)thio)-4H-1,2,4-triazol-3-yl)thiazole is closely related to a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, fluorine/chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
2-(4-Chlorophenyl)-4-(4-methyl-5-((3-(trifluoromethyl)benzyl)thio)-4H-1,2,4-triazol-3-yl)thiazole (CAS 338760-88-6) is a high-purity analytical reference standard with the molecular formula C20H14ClF3N4S2 and a molecular weight of 466.93 g/mol.
The molecular framework of 2-(4-Chlorophenyl)-4-(4-methyl-5-((3-(trifluoromethyl)benzyl)thio)-4H-1,2,4-triazol-3-yl)thiazole (C20H14ClF3N4S2) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 2-(4-Chlorophenyl)-4-(4-methyl-5-((3-(trifluoromethyl)benzyl)thio)-4H-1,2,4-triazol-3-yl)thiazole under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C20H14ClF3N4S2 |
| Molecular Weight | 466.93 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 4 |
| Sulfur Atoms | 2 |
Related Chlorophenyl Standards
- 2-((4-(4-Chlorophenyl)-5-(pyridin-4-yl)-4H-1,2,4-triazol-3-yl)thio)-1-(2,5-dimethoxyphenyl)ethanone (CAS 618880-40-3)
- 6-[(2E)-2-{[(4-chlorophenyl)methoxy]imino}ethyl]-1-[2-(3,4-dimethoxyphenyl)ethyl]-4-oxo-1,4-dihydropyrimidine-5-carbonitrile (CAS 303148-52-9)
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Recommended Standards
- Dalilesen Impurity 5 (CAS 1505485-09-5)
- 3-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]sulfanyl}-5-[(E)-2-[(2,4-dimethylphenyl)amino]ethenyl]-1,2-thiazole-4-carbonitrile (CAS 338413-06-2)
- Finerenone Impurity 287 (CAS CATO-C4X-2880287)
- 3-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]sulfanyl}-5-[(E)-2-[(3,4-dimethylphenyl)amino]ethenyl]-1,2-thiazole-4-carbonitrile (CAS 338413-00-6)
- 286474-59-7 4-Chloro-2-fluoro-3-formyltoluene 6-Chloro-2-fluoro-m-tolualdehyde 6-chloro-2-fluoro-3-methylbenzaldehyde (CAS 286474-59-7)
- KSHN00402-Rac (CAS 6856-43-5)
- Benzyl 2-chloro-4-hydroxybenzoate (CAS 115168-73-5)
- 5,5'-Dinitro-[1,1'-biphenyl]-3,3'-dicarboxylic acid (CAS 144949-59-7)
- Potassium (4-(9H-carbazol-9-yl)phenyl)trifluoroborate (CAS 1874177-91-9)
- Oclacitinib Impurity 14 (CAS CATO-C4X-301814)
- Boron sub-2,3-naphthalocyanine chloride (CAS 142710-56-3)
- N,N-Bis(2-(2-methoxyethoxy)ethyl)aniline (CAS 484679-02-9)
- 3-((2-Chloroallyl)oxy)azetidine (CAS 1342487-06-2)
- Semaglutide Impurity 164 (CAS CATO-C4X-2226164)
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