2-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]-2-(morpholin-4-yl)-2-[3-(trifluoromethyl)phenyl]acetonitrile CAS 338770-56-2
| CAS No. | 338770-56-2 |
| Molecular Formula | C19H14ClF6N3O |
| Molecular Weight | 449.78 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 2-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]-2-(morpholin-4-yl)-2-[3-(trifluoromethyl)phenyl]acetonitrile is closely related to a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies 2-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]-2-(morpholin-4-yl)-2-[3-(trifluoromethyl)phenyl]acetonitrile (CAS 338770-56-2), a certified reference material (molecular formula C19H14ClF6N3O, MW 449.78 g/mol) for analytical method development and quality control.
2-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]-2-(morpholin-4-yl)-2-[3-(trifluoromethyl)phenyl]acetonitrile (C19H14ClF6N3O) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 2-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]-2-(morpholin-4-yl)-2-[3-(trifluoromethyl)phenyl]acetonitrile under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C19H14ClF6N3O |
| Molecular Weight | 449.78 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 3 |
Related Chloro Standards
- N-(3-Chloro-4-methylphenyl)-2-[2,6-dinitro-4-(trifluoromethyl)phenyl]-hydrazinecarbothioamide (CAS 436133-68-5)
- 1-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-3a',4',8',8a'-tetrahydrospiro[piperidine-4,6'-[1,3]dioxepino[5,6-d]isoxazole]-3'-carbohydrazide (CAS 303152-99-0)
- 6-Chloro-N-(3,4-dichlorobenzyl)-4-(methylsulfonyl)-3,4-dihydro-2H-benzo[b][1,4]oxazine-2-carboxamide (CAS 866142-59-8)
- (2E)-1-{4-[(2-chloro-6-fluorophenyl)methoxy]phenyl}-3-{[4-(trifluoromethyl)phenyl]amino}prop-2-en-1-one (CAS 477871-16-2)
- Ethyl 6-chloro-4-((3-(trifluoromethyl)phenyl)sulfonyl)-3,4-dihydro-2H-benzo[b][1,4]oxazine-2-carboxylate (CAS 866134-62-5)
- 1-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]-4-(3-methyl-1-phenyl-1H-pyrazole-4-carbonyl)piperazine (CAS 321534-66-1)
- 5-(4-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)piperazin-1-yl)-3-methyl-1-phenyl-1H-pyrazole-4-carbaldehyde (CAS 400075-72-1)
- N-{2-[(2-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]amino}ethyl)amino]pyridin-3-yl}-4-methylbenzamide (CAS 338772-61-5)
Recommended Standards
- Ethyl N-[1-(2-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]amino}ethyl)-2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-carbonyl]carbamate (CAS 338409-46-4)
- (1,3-Dimethyltrimethylphenylimidazole-2-subunit) silver chloride (I) (CAS 873297-18-8)
- Des(dimethylamino)-4-hydrazone Demeclocycline (CAS 1177-81-7)
- N-(2-(2-Undecyl-4,5-dihydro-1H-imidazol-1-yl)ethyl)dodecanamide (CAS 71141-89-4)
- 3-Benzothiazol-2-yl-4-(4-nitro-phenyl)-but-3-enoic acid (CAS 748142-95-2)
- 3-amino-1-(cyclopropylmethyl)urea (CAS 1057393-54-0)
- (E)-3-(4-(Chlorosulfonyl)phenyl)acrylic acid (CAS 155378-73-7)
- tert-butyl N-[(tert-butoxy)carbonyl]-N-(2-chloro-9H-purin-6-yl)carbamate (CAS 1269786-75-5)
- 5-Isobutoxy-3-methylpentane-1-sulfonyl chloride (CAS 1490938-52-7)
- (5-Bromofuran-2-yl)methanamine hydrochloride (CAS 1803600-05-6)
- 2,4-Dichloro-3-fluorophenol (CAS 343-99-7)
- 3-Butoxy-4-cyanobenzenesulfonyl chloride (CAS 942199-54-4)
- 3-Chloro-10-methyl-9-phenyl-3,10-dihydroacridine (CAS 6321-70-6)
- Semaglutide Impurity 187 (CAS CATO-C4X-2226187)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com