4-[(2,4-Dichlorophenyl)sulfanyl]-5-methoxy-2-(pyridin-2-yl)pyrimidine CAS 338771-67-8
| CAS No. | 338771-67-8 |
| Molecular Formula | C16H11Cl2N3OS |
| Molecular Weight | 364.25 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 364.25 g/mol gives 4-[(2,4-Dichlorophenyl)sulfanyl]-5-methoxy-2-(pyridin-2-yl)pyrimidine distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
4-[(2,4-Dichlorophenyl)sulfanyl]-5-methoxy-2-(pyridin-2-yl)pyrimidine (CAS 338771-67-8) is a high-purity analytical reference standard with the molecular formula C16H11Cl2N3OS and a molecular weight of 364.25 g/mol.
The molecular framework of 4-[(2,4-Dichlorophenyl)sulfanyl]-5-methoxy-2-(pyridin-2-yl)pyrimidine (C16H11Cl2N3OS) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 4-[(2,4-Dichlorophenyl)sulfanyl]-5-methoxy-2-(pyridin-2-yl)pyrimidine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C16H11Cl2N3OS |
| Molecular Weight | 364.25 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Dichlorophenyl Standards
- 1-((2,5-Dichlorophenyl)sulfonyl)-N3,N3,N5,N5-tetramethyl-1H-1,2,4-triazole-3,5-diamine (CAS 478032-18-7)
- 4-[(2,6-Dichlorophenyl)sulfanyl]-5-methoxy-2-(pyridin-2-yl)pyrimidine (CAS 338772-29-5)
- Methyl 4-(4-(2,4-dichlorophenyl)thiazol-2-yl)benzoate (CAS 320420-82-4)
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Recommended Standards
- 1-[(4-Methoxyphenyl)methyl]-5-(tetramethyl-1,3,2-dioxaborolan-2-yl)-1,3-benzodiazole (CAS 2377610-75-6)
- 1,1,1-Trifluoro-4,4-bis(4,4,4-trifluorobutoxy)butane (CAS 933600-77-2)
- 4-Chloro-6-(((4-chlorophenyl)sulfinyl)methyl)-2-(pyridin-2-yl)pyrimidine (CAS 955962-38-6)
- (2R,3S,5R)-5-(5-Methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-2-((phosphonooxy)methyl)tetrahydrofuran-3-yl acetate (CAS 4304-30-7)
- 4,5,6,7-Tetrahydro-1H-pyrazolo[4,3-c]pyridin-3-amine dihydrochloride (CAS 1706440-13-2)
- 1-[2,5-Dimethyl-1-(2,2,4-trimethyl-2,3-dihydro-1-benzofuran-7-yl)-1H-pyrrol-3-yl]-2,2,2-trifluoro-1-ethanone (CAS 866008-61-9)
- Delamanid-D4 (CAS CATO-C4X-25141)
- 24240-04-8 beta-Allocryptopine Benzo(e)(1,3)dioxolo(4,5-k)(3)benzazecin-14(6H)-one, 5,7,8,15-tetrahydro-3,4-dimethoxy-6-methyl- 5,7,8,15-Tetrahydro-3,4-dimethoxy-6-methylbenzo(e)(1,3)dioxolo(4,5-k)(3)benzazecin-14(6H)-one gamma-Homochelidonine Fagarine I (CAS 24240-04-8)
- 1-(2-Chlorophenyl)-2-(4-hydroxypiperidin-1-yl)ethan-1-one (CAS 1338691-62-5)
- 1-Chloro-2-ethoxy-4-(trifluoromethyl)benzene (CAS 1378816-92-2)
- 6-methoxy-1-methyl-pyrrolo[2,3-b]pyridine (CAS 1872392-82-9)
- 2-(2,6-Dichlorophenyl)-1H-imidazo[4,5-c]pyridin-4-ol (CAS 1334411-80-1)
- n-((2-Methoxypyridin-3-yl)methyl)tetrahydrothiophen-3-amine (CAS 1178672-73-5)
- Tau Peptide (268-282) trifluoroacetate salt (CAS 330456-37-6)
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