N1-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)-N2-(2-nitrophenyl)ethane-1,2-diamine CAS 338772-75-1
| CAS No. | 338772-75-1 |
| Molecular Formula | C14H12ClF3N4O2 |
| Molecular Weight | 360.72 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including N1-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)-N2-(2-nitrophenyl)ethane-1,2-diamine.
N1-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)-N2-(2-nitrophenyl)ethane-1,2-diamine (CAS 338772-75-1), molecular formula C14H12ClF3N4O2 and molecular weight 360.72 g/mol, is a CATO reference standard with documented purity and traceability.
N1-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)-N2-(2-nitrophenyl)ethane-1,2-diamine (C14H12ClF3N4O2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), N1-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)-N2-(2-nitrophenyl)ethane-1,2-diamine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C14H12ClF3N4O2 |
| Molecular Weight | 360.72 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 4 |
Related N Standards
- 2-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]oxy}ethyl N-phenylcarbamate (CAS 1797034-56-0)
- 3-[(2-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]oxy}phenyl)amino]propanoic acid (CAS 1823183-34-1)
- 1-((3-Chloro-5-(trifluoromethyl)pyridin-2-yl)methyl)-N-((dimethylamino)methylene)-1H-1,2,3-triazole-4-carboxamide (CAS 1823194-86-0)
- N-(3-chloro-4-methoxybenzyl)-2-nitro-4-(trifluoromethyl)aniline (CAS 478259-85-7)
- 478039-26-8 5-{[2-(4-chloro-3-fluorophenoxy)phenyl]methylene}-2,4,6(1H,3H,5H)-pyrimidinetrione KS-000036HL (CAS 478039-26-8)
- N-[2-Chloro-5-(trifluoromethyl)phenyl]-2-{[(4-fluorophenyl)methyl]amino}acetamide (CAS 297150-42-6)
- 4-Chloro-1-(phenylsulfonyl)-5-(trifluoromethyl)-1H-pyrrolo[2,3-b]pyridine (CAS 1196507-57-9)
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Recommended Standards
- Copper dichloro[2,2-(2-imidazolidinylidene)bis[pyridine]]- (CAS 89509-06-8)
- 2,2',3,4-Tetrahydroxy-3'-sulfo-5'-chlorazobenzene 5-Chloro-2-hydroxy-3-[2-(3,4,5-trihydroxyphenyl)diazenyl]benzenesulfonic Acid 946153-47-5 Tetrahydroxyazon SCl (CAS 946153-47-5)
- 1,4,7,10,13,16-Hexathiacyclooctadecane (CAS 296-41-3)
- 6-({[(4-bromothiophen-2-yl)methyl](methyl)amino}methyl)-5-chloro-N-methylpyridin-2-amine (CAS 1411372-77-4)
- (S)-2-Amino-3-(5-(prop-2-yn-1-yloxy)-1H-indol-3-yl)propanoic acid (CAS 1858224-23-3)
- (R)-2-Amino-2-methylhept-6-enoic acid (CAS 1196090-89-7)
- 2-(2-methoxypyridin-4-yl)ethanamine;dihydrochloride (CAS 170026-02-5)
- 3-Thia-9-azaspiro[5.5]undecane 3,3-dioxide hydrochloride (CAS 1803582-31-1)
- 1,3-Bis(5-chloro-2-methylphenyl)urea (CAS 54965-12-7)
- 2-((Methylthio)methyl)-4-propylpyrimidine-5-carboxylic acid (CAS 1247673-52-4)
- tert-Butyl ((5-methylisoxazol-3-yl)methyl)carbamate (CAS 341030-45-3)
- [3-(Pyrrole-1-carbonyl)phenyl]boronic acid (CAS 1232815-56-3)
- (3aS,4S,5R,6aR)-4-(((tert-Butyldimethylsilyl)oxy)methyl)-5-((tetrahydro-2H-pyran-2-yl)oxy)hexahydropentalen-2(1H)-one (CAS 112168-22-6)
- Dulaglutide (CAS 923950-08-7)
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