(Z)-2-amino-N'-(2,4-dichlorobenzoyl)-4-methoxynicotinohydrazonamide CAS 338773-80-1
| CAS No. | 338773-80-1 |
| Molecular Formula | C14H13Cl2N5O2 |
| Molecular Weight | 354.19 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of (Z)-2-amino-N'-(2,4-dichlorobenzoyl)-4-methoxynicotinohydrazonamide is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
(Z)-2-amino-N'-(2,4-dichlorobenzoyl)-4-methoxynicotinohydrazonamide (CAS 338773-80-1) is a high-purity analytical reference standard with the molecular formula C14H13Cl2N5O2 and a molecular weight of 354.19 g/mol.
The molecular framework of (Z)-2-amino-N'-(2,4-dichlorobenzoyl)-4-methoxynicotinohydrazonamide (C14H13Cl2N5O2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C14H13Cl2N5O2 |
| Molecular Weight | 354.19 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 5 |
Related Z Standards
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Recommended Standards
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- 3-Bromo-6-fluoro-1-(phenylsulfonyl)-1H-indole (CAS 1504489-66-0)
- 1-(tert-butyl) 3-methyl 5-bromo-1H-indole-1,3-dicarboxylate (CAS 1100052-64-9)
- 5-(Chloromethyl)-1H-pyrazolo[3,4-c]pyridine (CAS 1206979-08-9)
- tert-Butyl (1-phenylbut-3-en-1-yl)carbamate (CAS 187974-79-4)
- N-(3,5-Dimethylphenyl)-3-(4-methoxyphenyl)-2-(2H-1,2,3,4-tetrazol-5-yl)propanamide (CAS 483993-06-2)
- Methyl 4-chloro-3-(hydroxy((3-hydroxy-2,3-dimethylbutan-2-yl)oxy)boranyl)benzoate (CAS 710350-72-4)
- Ethyl all cis-7,10,13,16,19-Docosapentaenoate (CAS 119818-40-5)
- Sacubitril Valsartan Sodium Impurity 2 (CAS 2806120-13-6)
- 2'-(5-Ethyl-3,4-diphenyl-1H-pyrazol-1-yl)-[1,1'-biphenyl]-3-ol (CAS 710354-39-5)
- Ethyl 2-((8-chloro-6-(trifluoromethyl)-[1,2,4]triazolo[4,3-a]pyridin-3-yl)thio)-2,2-difluoroacetate (CAS 1823182-39-3)
- Potassium (3-cyanophenyl)trifluoroborate (CAS 850623-46-0)
- Semaglutide impurity 93 (CAS CATO-C4X-222693)
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