(E)-2-(3-((2,6-difluorophenyl)amino)-1-(dimethylamino)allylidene)malononitrile CAS 338773-86-7
| CAS No. | 338773-86-7 |
| Molecular Formula | C14H12F2N4 |
| Molecular Weight | 274.27 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of (E)-2-(3-((2,6-difluorophenyl)amino)-1-(dimethylamino)allylidene)malononitrile is closely related to a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies (E)-2-(3-((2,6-difluorophenyl)amino)-1-(dimethylamino)allylidene)malononitrile (CAS 338773-86-7), a certified reference material (molecular formula C14H12F2N4, MW 274.27 g/mol) for analytical method development and quality control.
The molecular framework of (E)-2-(3-((2,6-difluorophenyl)amino)-1-(dimethylamino)allylidene)malononitrile (C14H12F2N4) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), (E)-2-(3-((2,6-difluorophenyl)amino)-1-(dimethylamino)allylidene)malononitrile meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C14H12F2N4 |
| Molecular Weight | 274.27 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 4 |
Related E Standards
- 1421262-35-2 2-(3,4-Difluorophenyl)-4-(4-pyridyl)thiazole MFCD22683012 (CAS 1421262-35-2)
- 3-(3-(2,6-Difluorophenyl)-1,2,4-oxadiazol-5-yl)pyridin-2-amine (CAS 1708168-88-0)
- 1-(2,4-Difluorophenyl)-3-(2,3-dimethylphenyl)propan-1-one (CAS 898793-33-4)
- 1-(2,4-Difluorophenyl)-3-(3,5-dimethylphenyl)propan-1-one (CAS 898781-10-7)
- 1-(3,4-Difluorophenyl)-3-(2,3-dimethylphenyl)propan-1-one (CAS 898793-35-6)
- 1-(3,4-Difluorophenyl)-3-(2,6-dimethylphenyl)propan-1-one (CAS 898755-30-1)
- 1-(3,4-Difluorophenyl)-3-(3,4-dimethylphenyl)propan-1-one (CAS 898779-87-8)
- 1-(3,5-Difluorophenyl)-3-(2,5-dimethylphenyl)propan-1-one (CAS 898754-10-4)
Recommended Standards
- (7R,8AS)-1,4-dioxooctahydropyrrolo[1,2-a]pyrazin-7-yl benzoate (CAS 879399-06-1)
- (E)-Diethyl (3-oxo-3-(thiophen-2-yl)prop-1-en-1-yl)phosphonate (CAS 2118313-76-9)
- (5Z)-5-[(Dimethylamino)methylidene]-4-methyl-3-(4-nitrophenyl)-2,5-dihydrofuran-2-one (CAS 338976-32-2)
- 1-(2-Methoxy-4-nitrophenyl)-2,5-dimethyl-1h-pyrrole-3-carbaldehyde (CAS 428827-99-0)
- 1-(5-Fluoropyridin-3-yl)cyclopropane-1-carbonitrile (CAS 1427010-14-7)
- 3-(4-Methoxyphenyl)-4-nitro-1H-pyrazole (CAS 18099-22-4)
- Sodium Oxamate (CAS 565-73-1)
- (S)-(4-Methylmorpholin-2-yl)methanamine (CAS 760914-29-2)
- 2-Amino-1-naphthalenesulfonic Acid (CAS 81-16-3)
- (4-Chlorophenyl)(thiophen-2-yl)methanamine (CAS 261925-23-9)
- 4-Aminobut-2-enoic acid (CAS 25747-40-4)
- 4-Phenyl-1H-pyrazolo[3,4-b]pyridin-3-ylamine (CAS 174713-63-4)
- Methyl 2-(1-(tert-Butoxycarbonyl)piperidin-4-yl)oxazole-4-carboxylate (CAS 922516-07-2)
- [Plus-β-Ala28]-Semaglutide (CAS CATO-C4X-2226221)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com