3-(4-Chloro-2-methylbenzenesulfonyl)-4,6-dimethyl-2-(2-methylpropoxy)pyridine CAS 338774-18-8
| CAS No. | 338774-18-8 |
| Molecular Formula | C18H22ClNO3S |
| Molecular Weight | 367.89 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 3-(4-Chloro-2-methylbenzenesulfonyl)-4,6-dimethyl-2-(2-methylpropoxy)pyridine is closely related to a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
3-(4-Chloro-2-methylbenzenesulfonyl)-4,6-dimethyl-2-(2-methylpropoxy)pyridine (CAS 338774-18-8), molecular formula C18H22ClNO3S and molecular weight 367.89 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 3-(4-Chloro-2-methylbenzenesulfonyl)-4,6-dimethyl-2-(2-methylpropoxy)pyridine (C18H22ClNO3S) is characterized by a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 3-(4-Chloro-2-methylbenzenesulfonyl)-4,6-dimethyl-2-(2-methylpropoxy)pyridine under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C18H22ClNO3S |
| Molecular Weight | 367.89 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Chloro Standards
- 2-Chloro-N-(2-(1-methyl-1H-pyrrol-2-yl)-2-(pyrrolidin-1-yl)ethyl)benzenesulfonamide (CAS 1049447-00-8)
- 3-((5-Chloro-2-methylphenyl)sulfonyl)-2-isobutoxy-4,6-dimethylpyridine (CAS 338774-19-9)
- 3-(3-Chloro-2-methylbenzenesulfonyl)-4,6-dimethyl-2-(2-methylpropoxy)pyridine (CAS 338412-20-7)
- 6-Chloro-N-((1-(2-methylpyridin-4-yl)piperidin-4-yl)methyl)-2,7-naphthyridin-1-amine (CAS 1956382-00-5)
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Recommended Standards
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- 2-(3-(((3-Chlorophenyl)thio)methyl)phenyl)benzo[d]thiazole (CAS 400087-87-8)
- 2-(Benzylthio)-N-(2-chlorobenzyl)benzamide (CAS 690646-51-6)
- 5-Butylindoline (CAS 67932-67-6)
- N-(indolin-5-yl)pyrazine-2-carboxamide (CAS 1405325-23-6)
- 2-(Phenylamino)phenol (CAS 644-71-3)
- (Chloromethyl)diphenylphosphine oxide (CAS 1806-49-1)
- 1,3-benzothiazol-7-ol (CAS 163298-73-5)
- Methyl 3-(2-aminophenoxy)thiophene-2-carboxylate (CAS 91041-21-3)
- Ethyl 2-(2-(pyridin-3-yl)thiazol-4-yl)acetate (CAS 80653-69-6)
- 2-(Aminomethyl)-3-{[(tert-butoxycarbonyl)amino]methyl}-1,1-biphenyl (CAS 927801-63-6)
- Tinidazole Impurity 15 (CAS 1889-59-4)
- Serpent Peptide (CAS 823202-99-9)
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