N-{5-acetyl-1-[(4-chlorophenyl)methyl]-6-methyl-2-oxo-1,2-dihydropyridin-3-yl}-4-chlorobenzamide CAS 338774-98-4
| CAS No. | 338774-98-4 |
| Molecular Formula | C22H18Cl2N2O3 |
| Molecular Weight | 429.30 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
N-{5-acetyl-1-[(4-chlorophenyl)methyl]-6-methyl-2-oxo-1,2-dihydropyridin-3-yl}-4-chlorobenzamide (CAS 338774-98-4), molecular formula C22H18Cl2N2O3 and molecular weight 429.30 g/mol, is a CATO reference standard with documented purity and traceability.
N-{5-acetyl-1-[(4-chlorophenyl)methyl]-6-methyl-2-oxo-1,2-dihydropyridin-3-yl}-4-chlorobenzamide (C22H18Cl2N2O3) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C22H18Cl2N2O3 |
| Molecular Weight | 429.30 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Recommended Standards
- (3Z)-3-{[(2,4-dichlorophenyl)methoxy]imino}-N-(4-phenoxyphenyl)propanamide (CAS 477851-47-1)
- 1,3-Diethyl 2-({[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]amino}methylidene)propanedioate (CAS 1024213-51-1)
- tert-Butyl 6-iodospiro[chroman-2,4'-piperidine]-1'-carboxylate (CAS 1086398-17-5)
- 2-(1-((4-(1,1,1,3,3,3-Hexafluoro-2-hydroxypropan-2-yl)phenyl)imino)ethyl)-3-hydroxy-1H-inden-1-one (CAS 1024227-89-1)
- 3-(3-Chlorophenyl)-4,5-dihydro-1,2-oxazole-5-carboxylic acid (CAS 1038696-53-5)
- sodium 1H-1,2,4-triazol-1-ylacetate (CAS 583858-39-3)
- 4-Bromo-5-fluoro-2-hydroxybenzonitrile (CAS 1805936-02-0)
- 1,8-Cineol-d3 1216822-66-0 (CAS 1216822-66-0)
- 898786-69-1 5-(5,5-Dimethyl-1,3-dioxan-2-yl)-1-[3-(trifluoromethyl)phenyl]pentan-1-one DTXSID60645951 (CAS 898786-69-1)
- (7-Methoxybenzo[c][1,2,5]thiadiazol-4-yl)methanamine (CAS 743379-78-4)
- 5-((2-Chlorophenoxy)methyl)-1,3,4-thiadiazol-2-amine (CAS 84138-74-9)
- 3-(o-Tolyl)-4,5-dihydro-1H-pyrazole (CAS 361442-92-4)
- tert-Butyl (S)-2-(hydroxymethyl)-4-methylpiperazine-1-carboxylate (CAS 1312755-68-2)
- Tirzepatide Impurity 15 (CAS CATO-C4X-324015)
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