N-(3-cyanothiophen-2-yl)-4-fluorobenzenesulfonamide CAS 338777-49-4
| CAS No. | 338777-49-4 |
| Molecular Formula | C11H7FN2O2S2 |
| Molecular Weight | 282.31 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 282.31 g/mol gives N-(3-cyanothiophen-2-yl)-4-fluorobenzenesulfonamide distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
N-(3-cyanothiophen-2-yl)-4-fluorobenzenesulfonamide (CAS 338777-49-4), molecular formula C11H7FN2O2S2 and molecular weight 282.31 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of N-(3-cyanothiophen-2-yl)-4-fluorobenzenesulfonamide (C11H7FN2O2S2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), N-(3-cyanothiophen-2-yl)-4-fluorobenzenesulfonamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C11H7FN2O2S2 |
| Molecular Weight | 282.31 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 2 |
Related N Standards
- N-(3-Cyanothiophen-2-yl)-2-(cyclohexylsulfanyl)acetamide (CAS 338777-51-8)
- N-(3-Cyanothiophen-2-yl)-5-(furan-2-yl)isoxazole-3-carboxamide (CAS 1251708-25-4)
- N-(2-cyanothiophen-3-yl)-4-methylbenzenesulfonamide (CAS 866009-12-3)
- N-(3-Cyanothiophen-2-yl)-2-(4-(methylthio)phenyl)acetamide (CAS 941971-30-8)
- N-(3-Cyanothiophen-2-yl)-4-(ethylthio)benzamide (CAS 898446-66-7)
- N-(3-Cyanothiophen-2-yl)-2-(methylthio)benzamide (CAS 896351-23-8)
- N-(3-Cyanothiophen-2-yl)-4-ethoxybenzamide (CAS 865546-06-1)
- N-(3-Cyanothiophen-2-yl)-3-(trifluoromethyl)benzamide (CAS 338777-37-0)
Recommended Standards
- Methyl 2-fluoro-2-(phenanthren-1-yl)propanoate (CAS 843614-85-7)
- Poly(oxy-1,2-ethanediyl), .alpha.-phosphono-.omega.-(decyloxy)- (CAS 9004-80-2)
- Ethyl 2-(4-(cyclopropylsulfonyl)phenyl)-2-oxoacetate (CAS 876063-40-0)
- tert-Butyl 2-(((2-fluoropyridin-3-yl)oxy)methyl)azetidine-1-carboxylate (CAS 887576-27-4)
- (S)-2-((((2-([1,1'-Biphenyl]-4-yl)propan-2-yl)oxy)carbonyl)amino)-3-(1H-imidazol-4-yl)propanoic acid (CAS 35897-36-0)
- 1-(3-Chloro-4-fluorophenyl)butane-1,3-dione (CAS 38440-12-9)
- tert-Butyl (5-bromo-2-chlorobenzyl)carbamate (CAS 478374-92-4)
- 3-Methylbenzo[d]isoxazol-7-ol (CAS 214760-33-5)
- 7-Bromothieno[3,2-d]pyrimidin-4(3H)-one (CAS 31169-25-2)
- Suvorexant impurity 29 (CAS 218621-86-4)
- 1-Methyl-1H-pyrazole-4,5-diamine; bis(sulfuric acid) (CAS 2126160-71-0)
- tert-Butyl 2-(((2-hydroxyethyl)thio)methyl)pyrrolidine-1-carboxylate (CAS 1353945-57-9)
- 6-Amino-1-ethyl-1,2,3,4-tetrahydroquinolin-2-one (CAS 233775-33-2)
- Polyphemusin II-Derived Peptide (CAS 229030-20-0)
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