N2-(4-chlorobenzyl)-N6,1-dimethyl-3,5-dinitro-1,4-dihydropyridine-2,6-diamine CAS 338777-94-9
| CAS No. | 338777-94-9 |
| Molecular Formula | C14H16ClN5O4 |
| Molecular Weight | 353.76 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of N2-(4-chlorobenzyl)-N6,1-dimethyl-3,5-dinitro-1,4-dihydropyridine-2,6-diamine is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies N2-(4-chlorobenzyl)-N6,1-dimethyl-3,5-dinitro-1,4-dihydropyridine-2,6-diamine (CAS 338777-94-9), a certified reference material (molecular formula C14H16ClN5O4, MW 353.76 g/mol) for analytical method development and quality control.
The molecular framework of N2-(4-chlorobenzyl)-N6,1-dimethyl-3,5-dinitro-1,4-dihydropyridine-2,6-diamine (C14H16ClN5O4) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C14H16ClN5O4 |
| Molecular Weight | 353.76 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 5 |
Related N Standards
- 2-(4-((4-Chlorobenzyl)oxy)phenyl)-5-(dimethylamino)oxazole-4-carbonitrile (CAS 844461-41-2)
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- 6-((2-Chlorobenzyl)thio)-3-(pyridin-4-yl)-[1,2,4]triazolo[4,3-b]pyridazine (CAS 868970-23-4)
- 6-((4-Chlorobenzyl)sulfonyl)-N-pentylpyridazin-3-amine (CAS 1040675-30-6)
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- 5-{[(2-Chlorobenzyl)thio]methyl}-4-cyclohexyl-4H-1,2,4-triazole-3-thiol (CAS 540518-43-2)
- 1-(2-Chlorobenzyl)-2-(2-chloropyridin-3-yl)-1H-benzo[d]imidazole (CAS 338411-31-7)
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Recommended Standards
- 4-((5-Chloro-6-oxo-1-phenyl-1,6-dihydropyridazin-4-yl)oxy)-3-methoxybenzonitrile (CAS 839685-39-1)
- N-(2-benzoyl-4-chlorophenyl)-2-fluorobenzamide (CAS 157488-11-4)
- 2-((2-Cyano-3-methylbutan-2-yl)amino)-2-oxoethyl 4-chloro-2-nitrobenzoate (CAS 878219-12-6)
- 2-((2-Chlorophenyl)thio)-N-(5-(trifluoromethyl)-1,3,4-thiadiazol-2-yl)acetamide (CAS 339013-82-0)
- 6-Bromo-1H-pyrrolo[2,3-b]pyridine-3-carboxylic acid (CAS 1190321-20-0)
- 2-Phenoxybenzotrifluoride (CAS 106877-16-1)
- 2,5-Dichloro-N-(2-methoxyethyl)benzenesulfonamide (CAS 329939-46-0)
- Salbutamol Impurity 96 (CAS 63416-80-8)
- N-Ethyl-2-oxo-N-phenyl-2H-chromene-3-carboxamide (CAS 313494-13-2)
- (2-Phenethylphenyl)methanol (CAS 835-78-9)
- 6-Nitroquinolin-3-ol (CAS 103029-76-1)
- Sacubitril Valsartan Sodium Impurity 3 (CAS 1907737-76-1)
- Z-Val-Ala-OH (CAS 24787-89-1)
- Des-Pro31-Tirzepatide (CAS CATO-CPTD788943)
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