3-{[(2-chloro-6-fluorophenyl)methyl]sulfanyl}-5-[(E)-2-(phenylamino)ethenyl]-1,2-thiazole-4-carbonitrile CAS 338778-75-9
| CAS No. | 338778-75-9 |
| Molecular Formula | C19H13ClFN3S2 |
| Molecular Weight | 401.91 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies 3-{[(2-chloro-6-fluorophenyl)methyl]sulfanyl}-5-[(E)-2-(phenylamino)ethenyl]-1,2-thiazole-4-carbonitrile (CAS 338778-75-9), a certified reference material (molecular formula C19H13ClFN3S2, MW 401.91 g/mol) for analytical method development and quality control.
Owing to a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, fluorine/chlorine substitution, 3-{[(2-chloro-6-fluorophenyl)methyl]sulfanyl}-5-[(E)-2-(phenylamino)ethenyl]-1,2-thiazole-4-carbonitrile is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 401.91 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 3-{[(2-chloro-6-fluorophenyl)methyl]sulfanyl}-5-[(E)-2-(phenylamino)ethenyl]-1,2-thiazole-4-carbonitrile under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C19H13ClFN3S2 |
| Molecular Weight | 401.91 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 2 |
Related chloro Standards
- N-(2-Chloro-4,6-dimethylphenyl)-2-((4-ethyl-5-(pyridin-2-yl)-4H-1,2,4-triazol-3-yl)thio)acetamide (CAS 578001-91-9)
- N-(2-Chloro-4,6-dimethylphenyl)-2-((4-ethyl-5-(pyridin-3-yl)-4H-1,2,4-triazol-3-yl)thio)acetamide (CAS 573931-96-1)
- N-(2-Chloro-4,6-dimethylphenyl)-2-((4-ethyl-5-(pyridin-4-yl)-4H-1,2,4-triazol-3-yl)thio)acetamide (CAS 587011-30-1)
- N-(5-Chloro-2-methoxyphenyl)-2-((1-(2,3-dimethylphenyl)-1H-imidazol-2-yl)thio)acetamide (CAS 851131-72-1)
- (2E)-3-{4-[(2-chloro-6-fluorophenyl)methoxy]phenyl}-N-cycloheptylprop-2-enamide (CAS 477870-71-6)
- 2-(2-(3-CHLORO-2-METHYLPHENYLSULFONAMIDO)THIAZOL-4-YL)-N,N-DIETHYLACETAMIDE (CAS 376638-65-2)
- 2-(3-(((4-Chloro-5-cyano-6-(thiophen-2-yl)pyrimidin-2-yl)thio)methyl)phenyl)acetic acid (CAS 2428519-99-5)
- (2E)-3-{4-[(2-chloro-6-fluorophenyl)methoxy]phenyl}-N-[(thiophen-2-yl)methyl]prop-2-enamide (CAS 477870-70-5)
Recommended Standards
- 2-{[5-(4-tert-Butylphenyl)-4-(4-chlorophenyl)-4h-1,2,4-triazol-3-yl]sulfanyl}acetic acid (CAS 893727-59-8)
- 2-((5-(4-(Tert-butyl)phenyl)-1,3,4-oxadiazol-2-yl)thio)-N-(4-chlorophenyl)acetamide (CAS 337503-47-6)
- 2-((4-(4-Chlorophenyl)-5-(pyridin-4-yl)-4H-1,2,4-triazol-3-yl)thio)-N,N-diethylacetamide (CAS 476483-81-5)
- 1-(4-Chlorobenzyl)-4,6-dimethyl-3-(m-tolylsulfonyl)pyridin-2(1H)-one (CAS 338398-02-0)
- 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine-N-[4-(p-maleimidophenyl)butyramide] (sodium salt) 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine-N-[4-(p-maleimidophenyl)butyramide] (sodium salt) 18:1 MPB PE 384835-49-8 (CAS 384835-49-8)
- (2S,4S)-2-methyltetrahydropyran-4-ol (CAS 82110-13-2)
- 1-(6-Fluoro-2-pyridinyl)-4-(1H-1,2,4-triazol-1-yl)-1H-pyrazol-5-ol (CAS 1007237-14-0)
- (S)-tert-Butyl 3-{[(3-bromophenyl)methyl]amino}piperidine-1-carboxylate (CAS 1338222-17-5)
- (2R)-2-(propan-2-yl)morpholine (CAS 792886-64-7)
- 2,3,4,5-Tetrahydrobenzo[b]oxepin-4-amine oxalate (CAS 1956380-62-3)
- Methyl 5-(Chloromethyl)nicotinate Hydrochloride (CAS 179072-14-1)
- 3-(Piperidin-1-yl)propyl 2-butoxy-4-(butylamino)benzoate (CAS 100311-20-4)
- 1,1-dimethyl-2-phenylguanidine hydroiodide (CAS 69561-87-1)
- Insulin Degludec Impurity 25 (CAS CATO-C4X-215725)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com