N-[(1E)-{[(2,6-dichlorophenyl)methoxy]imino}methyl]-1-(pyrimidin-2-yl)piperidine-4-carboxamide CAS 338780-54-4
| CAS No. | 338780-54-4 |
| Molecular Formula | C18H19Cl2N5O2 |
| Molecular Weight | 408.28 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 408.28 g/mol gives N-[(1E)-{[(2,6-dichlorophenyl)methoxy]imino}methyl]-1-(pyrimidin-2-yl)piperidine-4-carboxamide distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
N-[(1E)-{[(2,6-dichlorophenyl)methoxy]imino}methyl]-1-(pyrimidin-2-yl)piperidine-4-carboxamide (CAS 338780-54-4), molecular formula C18H19Cl2N5O2 and molecular weight 408.28 g/mol, is a CATO reference standard with documented purity and traceability.
N-[(1E)-{[(2,6-dichlorophenyl)methoxy]imino}methyl]-1-(pyrimidin-2-yl)piperidine-4-carboxamide (C18H19Cl2N5O2) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C18H19Cl2N5O2 |
| Molecular Weight | 408.28 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 5 |
Recommended Standards
- 4-Chloro-N-(2-chloro-5-(2-morpholinoacetamido)phenyl)benzamide (CAS 500001-93-4)
- N-[(1E)-{[(3,4-dichlorophenyl)methoxy]imino}methyl]-1-(pyrimidin-2-yl)piperidine-4-carboxamide (CAS 338780-62-4)
- 4-{4-[(2,4-dichlorophenyl)methoxy]phenyl}-2-(pyridin-4-yl)pyrimidine (CAS 478039-29-1)
- Palonosetron Impurity 38 (CAS CATO-C4X-110538)
- (+)-Muscarine Iodide (CAS 24570-49-8)
- Ethyl (S)-4-(piperidin-2-yl)benzoate (CAS 1388117-52-9)
- Ethyl 4-phenyl-2-(pyridin-4-yl)thiazole-5-carboxylate (CAS 228413-59-0)
- 3-Bromo-2-nitrobenzenesulphonamide (CAS 1261521-33-8)
- 4-(1,3-Dithiolan-2-yl)-2-methoxy-6-nitrophenyl 4-(tert-butyl)benzoate (CAS 298215-43-7)
- 2-Chlorobenzo[d]oxazole-6-carbaldehyde (CAS 1780575-73-6)
- 2-Chloro-6-ethylisonicotinoyl chloride (CAS 89938-71-6)
- 1,1-Diphenyl-2-(phenylsulfonyl)ethan-1-ol (CAS 59826-93-6)
- N-(4-(N-(4-Iodophenyl)sulfamoyl)phenyl)acetamide (CAS 19837-94-6)
- D-Pro38-Tirzepatide (CAS CATO-CPTD788901)
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