1-(4-Chlorobenzyl)-6-oxo-N-(4-(trifluoromethoxy)phenyl)-1,6-dihydropyridine-3-carboxamide CAS 338783-27-0
| CAS No. | 338783-27-0 |
| Molecular Formula | C20H14ClF3N2O3 |
| Molecular Weight | 422.78 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO supplies 1-(4-Chlorobenzyl)-6-oxo-N-(4-(trifluoromethoxy)phenyl)-1,6-dihydropyridine-3-carboxamide (CAS 338783-27-0), a certified reference material (molecular formula C20H14ClF3N2O3, MW 422.78 g/mol) for analytical method development and quality control.
The molecular framework of 1-(4-Chlorobenzyl)-6-oxo-N-(4-(trifluoromethoxy)phenyl)-1,6-dihydropyridine-3-carboxamide (C20H14ClF3N2O3) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
As a certified reference material (CRM), 1-(4-Chlorobenzyl)-6-oxo-N-(4-(trifluoromethoxy)phenyl)-1,6-dihydropyridine-3-carboxamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C20H14ClF3N2O3 |
| Molecular Weight | 422.78 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
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Recommended Standards
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- Ethyl 2-amino-4-(2-chloro-5-nitrophenyl)-6-(hydroxymethyl)-8-oxo-4H,8H-pyrano[3,2-b]pyran-3-carboxylate (CAS 674804-97-8)
- 7-{[(4-chlorophenyl)methyl]sulfanyl}-2,4-bis(trifluoromethyl)-1,8-naphthyridine (CAS 477851-92-6)
- Phosphine, 1,5-pentanediylbis[bis(3,5-dimethylphenyl)- (CAS 220185-38-6)
- 2-(2-(Dibenzo[b,d]furan-3-ylamino)-2-oxoethoxy)acetic acid (CAS 891040-98-5)
- 3-Methoxy-4-methylbenzonitrile (CAS 3556-60-3)
- N-isopropyl-N-(4-methoxybenzyl)glycine (CAS 1179945-25-5)
- (S)-5-(Bromomethyl)pyrrolidin-2-one (CAS 72479-05-1)
- Lasmiditan Impurity 27 (CAS CATO-C4X-247827)
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- Staphyloferrin A (CAS 127902-98-1)
- 4-[(2-Bromoacetyl)amino]-N-propylbenzamide (CAS 1138442-94-0)
- Acetyl Tetrapeptide-5 (CAS 820959-17-9)
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