2-(4-(1H-pyrrol-1-yl)phenoxy)-3-chloro-5-(trifluoromethyl)pyridine CAS 338785-63-0
| CAS No. | 338785-63-0 |
| Molecular Formula | C16H10ClF3N2O |
| Molecular Weight | 338.71 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 2-(4-(1H-pyrrol-1-yl)phenoxy)-3-chloro-5-(trifluoromethyl)pyridine is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies 2-(4-(1H-pyrrol-1-yl)phenoxy)-3-chloro-5-(trifluoromethyl)pyridine (CAS 338785-63-0), a certified reference material (molecular formula C16H10ClF3N2O, MW 338.71 g/mol) for analytical method development and quality control.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, 2-(4-(1H-pyrrol-1-yl)phenoxy)-3-chloro-5-(trifluoromethyl)pyridine is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 338.71 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C16H10ClF3N2O |
| Molecular Weight | 338.71 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
Related H Standards
- 2-(3-(1H-pyrrol-1-yl)thiophen-2-yl)-5-(benzylthio)-1,3,4-oxadiazole (CAS 478077-12-2)
- 5-(1H-Pyrrol-1-yl)-1-[4-(trifluoromethoxy)phenyl]-1H-pyrazole-4-carboxylic acid (CAS 1232794-76-1)
- 1-(2-((6-(1H-Pyrrol-1-yl)pyridazin-3-yl)amino)ethyl)-3-(o-tolyl)urea (CAS 1396874-16-0)
- (4-(1H-Pyrrol-1-yl)pyridin-2-yl)(4-(pyrimidin-2-yl)piperazin-1-yl)methanone (CAS 1421454-11-6)
- 2-((4-(1H-Pyrrol-1-yl)-4H-1,2,4-triazol-3-yl)thio)-N-(2-methoxy-5-methylphenyl)acetamide (CAS 903360-53-2)
- (4-(1H-Pyrrol-1-yl)phenyl)(3-((dimethylamino)methyl)-1,4-thiazepan-4-yl)methanone (CAS 1448044-51-6)
- 2-(2-(1H-Pyrrol-1-yl)thiazol-4-yl)-N-(4,5,6,7-tetrahydrobenzo[d]thiazol-2-yl)acetamide (CAS 1172559-35-1)
- (4-(1H-pyrrol-1-yl)phenyl)(4-benzylpiperazin-1-yl)methanone (CAS 439097-48-0)
Recommended Standards
- 2-(2-Chloro-4-(trifluoromethyl)phenyl)-4-methylphthalazin-1(2H)-one (CAS 551921-15-4)
- 2-(4-Chloro-2-methylphenoxy)-3-(trifluoromethyl)quinoxaline (CAS 338773-64-1)
- 2-(2-Chloro-4-(1H-pyrrol-1-yl)phenoxy)-5-(trifluoromethyl)pyridine (CAS 338397-70-9)
- 2-(Chloromethyl)-3-(3-(trifluoromethyl)phenyl)quinazolin-4(3H)-one (CAS 312510-67-1)
- Rel-(1R,2R)-2-(pyridin-3-yl)cyclohexan-1-ol (CAS 1807914-21-1)
- (2,4-Dimethoxybenzyl)hydrazine (CAS 401633-35-0)
- (1-(Thieno[2,3-d]pyrimidin-4-yl)piperidin-4-yl)methanol (CAS 1086376-68-2)
- 2-(2-(P-tolyl)hydrazine-1-carbonyl)benzoic acid (CAS 109310-97-6)
- Methyl 6-(tert-butylthio)-2-methylnicotinate (CAS 1355215-56-3)
- 2-(2-Bromophenyl)-5-chloro-4H-benzo[d][1,3]oxazin-4-one (CAS 1234707-32-4)
- 5,6-difluoronaphthalen-2-ol (CAS 321319-15-7)
- 5-Chloro-2-[5-(chloromethyl)-1,3,4-oxadiazol-2-yl]pyridine (CAS 1009562-61-1)
- N-(4-ethoxyphenyl)piperidine-1-carboxamide (CAS 36879-55-7)
- [α-Glu](Sidechain trans-position)-Liraglutide (CAS CATO-C4X-199240)
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