3-(Quinolin-8-yloxy)-5-(trifluoromethyl)pyridine-2-carbonitrile CAS 338791-72-3
| CAS No. | 338791-72-3 |
| Molecular Formula | C16H8F3N3O |
| Molecular Weight | 315.25 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
CATO supplies 3-(Quinolin-8-yloxy)-5-(trifluoromethyl)pyridine-2-carbonitrile (CAS 338791-72-3), a certified reference material (molecular formula C16H8F3N3O, MW 315.25 g/mol) for analytical method development and quality control.
The molecular framework of 3-(Quinolin-8-yloxy)-5-(trifluoromethyl)pyridine-2-carbonitrile (C16H8F3N3O) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C16H8F3N3O |
| Molecular Weight | 315.25 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related Quinolin Standards
- 2-(Quinolin-2-yl)-1-(3-(trifluoromethyl)phenyl)ethan-1-one (CAS 849021-38-1)
- 2-(Quinolin-2-yl)-1-(4-(trifluoromethyl)phenyl)ethan-1-one (CAS 283597-72-8)
- 2-(Quinolin-4-yl)-1-(4-(trifluoromethyl)phenyl)ethan-1-one (CAS 476472-22-7)
- 4-[2-(Quinolin-3-yl)-1h-indol-3-yl]butan-1-amine (CAS 556778-31-5)
- 1,3-Di(quinolin-6-yl)urea (CAS 532-05-8)
- 2-((2-(Quinolin-8-yl)hydrazono)methyl)quinolin-8-ol (CAS 24430-56-6)
- Quinolin-8-yl naphthalen-1-ylcarbamate (CAS 20842-57-3)
- Quinolin-2-ylmethyl 4-methylbenzenesulfonate (CAS 19820-77-0)
Recommended Standards
- 3-(Methoxymethyl)-4-({[4-(trifluoromethoxy)phenyl]amino}methylidene)-4,5-dihydro-1H-pyrazol-5-one (CAS 338394-41-5)
- 4-{[3-(trifluoromethyl)quinoxalin-2-yl]oxy}benzonitrile (CAS 338773-68-5)
- 3-((7-Methoxy-2-(trifluoromethyl)quinazolin-4-yl)amino)propanoic acid (CAS 929455-33-4)
- Ethyl 5-amino-1-(4-(trifluoromethoxy)phenyl)-1h-pyrazole-4-carboxylate (CAS 400073-87-2)
- 2-(Difluoromethyl)-4-methoxy-6-methyl-3-nitropyridine (CAS 1805465-10-4)
- 2-Amino-1-((S)-2-((dimethylamino)methyl)piperidin-1-yl)propan-1-one (CAS 1354024-56-8)
- 6-Fluoro-2-(3,3,3-trifluoropropyloxyl)nitrobenzene (CAS 1552511-79-1)
- Ethyl 5-(3-(dimethylamino)-2-hydroxypropoxy)-2-phenylbenzofuran-3-carboxylate (CAS 380341-26-4)
- 3-Deoxygalanthamine (CAS 312920-69-7)
- (S)-3-amino-4-(2-chlorophenyl)butanoic acid hydrochloride (CAS 331763-52-1)
- 1-(Benzo[d][1,3]dioxol-5-yl)-5-(methoxymethyl)-1H-1,2,3-triazole-4-carboxylic acid (CAS 1267107-67-4)
- 2-(5-Amino-3-(5-iodothiophen-3-yl)-1h-pyrazol-1-yl)ethan-1-ol (CAS 1517932-50-1)
- 2-Methoxy-5-(methoxymethyl)phenylboronic acid (CAS 1332504-32-1)
- Des-Ile27-Tirzepatide (CAS CATO-CPTD788946)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com