2,2-Difluoro-N-(4-methylphenyl)-2-[3-(trifluoromethyl)phenoxy]acetamide CAS 338792-11-3

Purity 97%+In StockPharmaceutical Standards
CAS No.338792-11-3
Molecular FormulaC16H12F5NO2
Molecular Weight345.26 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

2,2-Difluoro-N-(4-methylphenyl)-2-[3-(trifluoromethyl)phenoxy]acetamide CAS 338792-11-3 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 345.26 g/mol gives 2,2-Difluoro-N-(4-methylphenyl)-2-[3-(trifluoromethyl)phenoxy]acetamide distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

2,2-Difluoro-N-(4-methylphenyl)-2-[3-(trifluoromethyl)phenoxy]acetamide (CAS 338792-11-3) is a high-purity analytical reference standard with the molecular formula C16H12F5NO2 and a molecular weight of 345.26 g/mol.

Structurally, 2,2-Difluoro-N-(4-methylphenyl)-2-[3-(trifluoromethyl)phenoxy]acetamide (C16H12F5NO2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 9.0, corresponding to approximately 9 ring(s) or double-bond equivalent(s). With a molecular weight of 345.26 g/mol, it falls into the moderately-high-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

CATO manufactures 2,2-Difluoro-N-(4-methylphenyl)-2-[3-(trifluoromethyl)phenoxy]acetamide under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

Molecular FormulaC16H12F5NO2
Molecular Weight345.26 g/mol
AppearancePale yellow to yellow crystalline powder. (slight halide-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)9.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)2025
Halogen ContentF-containing
Nitrogen Atoms1

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