N-(4-chlorophenyl)-2,2-difluoro-2-(4-fluorophenoxy)acetamide CAS 338792-33-9
| CAS No. | 338792-33-9 |
| Molecular Formula | C14H9ClF3NO2 |
| Molecular Weight | 315.67 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures N-(4-chlorophenyl)-2,2-difluoro-2-(4-fluorophenoxy)acetamide under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
N-(4-chlorophenyl)-2,2-difluoro-2-(4-fluorophenoxy)acetamide (CAS 338792-33-9) is a high-purity analytical reference standard with the molecular formula C14H9ClF3NO2 and a molecular weight of 315.67 g/mol.
N-(4-chlorophenyl)-2,2-difluoro-2-(4-fluorophenoxy)acetamide (C14H9ClF3NO2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C14H9ClF3NO2 |
| Molecular Weight | 315.67 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
Related N Standards
- N-[(4-Chlorophenyl)methyl]-2,2,2-trifluoro-N-(pyrazin-2-yl)acetamide (CAS 866042-29-7)
- 4-(2-Chlorophenyl)-2-(3-nitrophenyl)-1,2-dihydro-3H-pyrazol-3-one (CAS 400076-67-7)
- 4-(3-Chlorophenyl)-2-(3-nitrophenyl)-1,2-dihydro-3H-pyrazol-3-one (CAS 400075-13-0)
- 4-(4-Chlorophenyl)-2-(3-nitrophenyl)-1,2-dihydro-3H-pyrazol-3-one (CAS 400075-12-9)
- 5-(2-Chlorophenyl)-N-(2-fluorophenyl)furan-2-carboxamide (CAS 618400-50-3)
- 5-(2-Chlorophenyl)-N-(4-fluorophenyl)furan-2-carboxamide (CAS 618400-45-6)
- N1-(2-Chlorophenyl)indoline-1,2-dicarboxamide (CAS 1101206-00-1)
- Ethyl 2-(2-chlorophenyl)-7-methylpyrazolo[1,5-a]pyrimidine-6-carboxylate (CAS 1332506-36-1)
Recommended Standards
- Methyl 4-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]benzenecarboxylate (CAS 885949-65-5)
- N-[2-Chloro-5-(trifluoromethyl)phenyl]-2-hydroxybenzamide (CAS 5683-92-1)
- 2-(4-Chlorophenoxy)-2,2-difluoro-N-(4-fluorophenyl)acetamide (CAS 250714-55-7)
- Sorafenib Impurity 4 (CAS 871555-75-8)
- 7-Methoxy-4-methylquinoline (CAS 6238-12-6)
- N-(3-Aminophenyl)-2-phenoxybutanamide (CAS 1020722-36-4)
- 1-((1,3,5-Trimethyl-1H-pyrazol-4-yl)sulfonyl)pyrrolidin-3-amine hydrochloride (CAS 1830788-91-4)
- N-(3-ethoxy-4-nitrophenyl)acetamide (CAS 871895-08-8)
- 5,5-Bis(chloromethyl)-2-phenyl-1,3-dioxane (CAS 6103-09-9)
- Trazodone Impurity 48 HCl (CAS CATO-C4X-177248)
- 3-Morpholinoisonicotinaldehyde (CAS 1707581-11-0)
- 1-Benzyl-3-oxoazepane (CAS 146407-32-1)
- Methyl 5-isopropyl-3-(2-(trifluoromethoxy)phenyl)isoxazole-4-carboxylate (CAS 1097776-52-7)
- Des-[Gly]31-Semaglutide (CAS CATO-C4X-2226156)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com