2,2-Difluoro-2-(4-fluorophenoxy)-1-(pyrrolidin-1-yl)ethan-1-one CAS 338792-59-9

Purity 97%+In StockPharmaceutical Standards
CAS No.338792-59-9
Molecular FormulaC12H12F3NO2
Molecular Weight259.22 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

2,2-Difluoro-2-(4-fluorophenoxy)-1-(pyrrolidin-1-yl)ethan-1-one CAS 338792-59-9 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 259.22 g/mol gives 2,2-Difluoro-2-(4-fluorophenoxy)-1-(pyrrolidin-1-yl)ethan-1-one distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

CATO supplies 2,2-Difluoro-2-(4-fluorophenoxy)-1-(pyrrolidin-1-yl)ethan-1-one (CAS 338792-59-9), a certified reference material (molecular formula C12H12F3NO2, MW 259.22 g/mol) for analytical method development and quality control.

Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution, 2,2-Difluoro-2-(4-fluorophenoxy)-1-(pyrrolidin-1-yl)ethan-1-one is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 259.22 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 2,2-Difluoro-2-(4-fluorophenoxy)-1-(pyrrolidin-1-yl)ethan-1-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC12H12F3NO2
Molecular Weight259.22 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)6.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)2025
Halogen ContentF-containing
Nitrogen Atoms1

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