1-(2-(4-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)piperazin-1-yl)ethyl)-3-(4-chlorophenyl)urea CAS 338792-85-1
| CAS No. | 338792-85-1 |
| Molecular Formula | C19H20Cl2F3N5O |
| Molecular Weight | 462.30 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
1-(2-(4-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)piperazin-1-yl)ethyl)-3-(4-chlorophenyl)urea (C19H20Cl2F3N5O) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
1-(2-(4-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)piperazin-1-yl)ethyl)-3-(4-chlorophenyl)urea (CAS 338792-85-1), molecular formula C19H20Cl2F3N5O and molecular weight 462.30 g/mol, is a CATO reference standard with documented purity and traceability.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C19H20Cl2F3N5O |
| Molecular Weight | 462.30 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 5 |
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Recommended Standards
- Methyl 4-{4-[2-(4-bromophenyl)-2-oxoethyl]piperazin-1-yl}-3-nitrobenzoate (CAS 478246-67-2)
- N-(2-Benzoylphenyl)-2-(6-bromo-4-oxoquinazolin-3(4H)-yl)acetamide (CAS 853318-90-8)
- N1-[3-(trifluoromethyl)phenyl]-2-{[5-(2,6-dichloro-4-pyridyl)-4-methyl-4H-1,2,4-triazol-3-yl]thio}acetamide (CAS 680216-62-0)
- Tepotinib impurity 12 (CAS CATO-C4X-337412)
- 1-(2,3-Dihydro-benzo[1,4]dioxin-6-yl)-2-phenyl-ethylamine hydrochloride (CAS 212714-12-0)
- 2-[5-[(3-Methyl-3-oxetanyl)methoxy]-1-benzimidazolyl]-8-quinolinol (CAS 816463-38-4)
- (1R,4S)-Camphorquinone Monooxime (CAS 22472-58-8)
- N-(4-chlorophenyl)-2,5-dihydro-3-Thiophenesulfonamide,1,1-dioxide (CAS 880449-90-1)
- Leuprorelin Impurity 47 (CAS CATO-C4X-182247)
- 6-Fluoro-1,1,4,4,7-pentamethyl-1,2,3,4-tetrahydronaphthalene (CAS 410528-74-4)
- L-Dicentrine (CAS 28832-07-7)
- Methyl 2-iodo-6-nitrobenzoate (CAS 5471-78-3)
- Methyl 2-(((4-cyano-5-methylisothiazol-3-yl)thio)methyl)benzoate (CAS 338778-07-7)
- Semaglutide impurity 247 (CAS CATO-C4X-2226247)
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