4-[(4-Fluorophenyl)methyl]thiomorpholine-3,5-dione CAS 338794-65-3
| CAS No. | 338794-65-3 |
| Molecular Formula | C11H10FNO2S |
| Molecular Weight | 239.27 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 4-[(4-Fluorophenyl)methyl]thiomorpholine-3,5-dione.
CATO supplies 4-[(4-Fluorophenyl)methyl]thiomorpholine-3,5-dione (CAS 338794-65-3), a certified reference material (molecular formula C11H10FNO2S, MW 239.27 g/mol) for analytical method development and quality control.
The molecular framework of 4-[(4-Fluorophenyl)methyl]thiomorpholine-3,5-dione (C11H10FNO2S) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 4-[(4-Fluorophenyl)methyl]thiomorpholine-3,5-dione meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C11H10FNO2S |
| Molecular Weight | 239.27 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Fluorophenyl Standards
- 3-(2-Fluorophenyl)-4-methyl-5-(methylsulfinyl)-4H-1,2,4-triazole (CAS 116850-53-4)
- 5-(4-Fluorophenyl)-3,4-dihydro-2h-1,4-thiazine-3-carboxylic acid (CAS 1190102-74-9)
- (4-(4-Fluorophenyl)-5-(methylthio)-4H-1,2,4-triazol-3-yl)methanol (CAS 1707668-05-0)
- 2-(4-Fluorophenyl)-3-(methylsulfonyl)-1H-pyrrole (CAS 1708289-26-2)
- 2-(3-Fluorophenyl)-3-(methylsulfonyl)-1H-pyrrole (CAS 1710293-66-5)
- 2-(2-Fluorophenyl)-3-(methylsulfonyl)-1H-pyrrole (CAS 1710472-28-8)
- 4-(4-Fluorophenyl)-2-methylthiomorpholine-3,5-dione (CAS 344266-02-0)
- Ethyl 3-{[2-(4-fluorophenyl)ethyl]amino}propanoate (CAS 1099610-28-2)
Recommended Standards
- 4,5-Diphenyl-4,5-dihydroisoxazol-5-ol (CAS 61184-62-1)
- 4-{5-[(3-fluoropropyl)sulfanyl]-1,3,4-oxadiazol-2-yl}pyridine (CAS 477856-92-1)
- 4,4-Diphenyloxazolidin-2-one (CAS 7480-33-3)
- 4-Amino-3-(2,4-dimethoxyphenyl)butanoic acid (CAS 79050-39-8)
- m-PEG6-thiol (CAS 441771-60-4)
- 3-Bromo-4-(2-(pyrrolidin-1-yl)ethoxy)benzaldehyde (CAS 938310-95-3)
- 3-Methyl-7,8-dihydroquinolin-5(6H)-one (CAS 60247-70-3)
- 2-((3-Methyl-3H-[1,2,3]triazolo[4,5-d]pyrimidin-7-yl)thio)-N-(4-methylbenzyl)acetamide (CAS 1058495-72-9)
- N-(3-Chlorophenyl)-6-methoxy-2H-chromene-3-carboxamide (CAS 478048-33-8)
- 1-Cyclohexyl-3-nitrobenzene (CAS 33176-38-4)
- 2-Methoxyethyl ((4-nitrophenoxy)carbonyl)-L-phenylalaninate (CAS 328406-65-1)
- 4-Bromobenzoic-d4 Acid (CAS 787624-24-2)
- Ethyl 2-(5-bromo-3-methoxypyridin-2-yl)acetate (CAS 1805567-99-0)
- Tirzepatide Impurity 43 (CAS CATO-C4X-324043)
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