3-Chloro-2-{2-phenylpyrazolo[1,5-a]pyrimidin-6-yl}-5-(trifluoromethyl)pyridine CAS 338953-39-2
| CAS No. | 338953-39-2 |
| Molecular Formula | C18H10ClF3N4 |
| Molecular Weight | 374.75 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
3-Chloro-2-{2-phenylpyrazolo[1,5-a]pyrimidin-6-yl}-5-(trifluoromethyl)pyridine (CAS 338953-39-2) is a high-purity analytical reference standard with the molecular formula C18H10ClF3N4 and a molecular weight of 374.75 g/mol.
Based on its molecular formula C18H10ClF3N4, 3-Chloro-2-{2-phenylpyrazolo[1,5-a]pyrimidin-6-yl}-5-(trifluoromethyl)pyridine contains a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 374.75 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C18H10ClF3N4 |
| Molecular Weight | 374.75 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 4 |
Related Chloro Standards
- 7-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-2-phenylpyrazolo[1,5-a]pyrimidine (CAS 1092345-56-6)
- 3-Chloro-2-{3-phenylpyrazolo[1,5-a]pyrimidin-7-yl}-5-(trifluoromethyl)pyridine (CAS 1092345-99-7)
- (S)-3-Chloro-7-(2-(hydroxymethyl)morpholino)-2-methyl-5-(trifluoromethyl)-1H-pyrrolo[3,2-b]pyridine-6-carbonitrile (CAS 2227425-05-8)
- 1-(3-Chloro-4-fluorophenyl)-3-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)-1H-pyrazole-5-carboxylic acid (CAS 618383-07-6)
- 4-((2-(5-Chloro-2-fluorophenyl)-5-methoxypyrimidin-4-yl)amino)nicotinic acid (CAS 674793-52-3)
- 5-({4-[(2-chloro-6-fluorophenyl)methoxy]phenyl}methylidene)-1,3-diazinane-2,4,6-trione (CAS 430469-95-7)
- 6-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-3-phenylpyrazolo[1,5-a]pyrimidine (CAS 338953-56-3)
- N-(1-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)-1H-pyrrol-2-yl)morpholine-4-carboxamide (CAS 338407-68-4)
Recommended Standards
- 2-(5-(4-Chlorophenyl)-1H-pyrazol-1-yl)-3-(trifluoromethyl)quinoxaline (CAS 321538-11-8)
- 4-({[(4-chlorobenzoyl)amino]carbonyl}amino)-3-fluorobenzene-1-sulphonyl fluoride (CAS 284674-50-6)
- (Z)-[1-(Pyrazin-2-yl)ethylidene]amino 3-(2-chloro-6-fluorophenyl)-5-methyl-1,2-oxazole-4-carboxylate (CAS 866050-53-5)
- 3-Amino-1-(benzo[d][1,3]dioxol-5-yl)-5,6,7,7a-tetrahydro-1H-indol-2(4H)-one (CAS 53446-25-6)
- 7-chloro-2-methyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1,6-naphthyridine (CAS 2772659-30-8)
- 3-(Benzyloxy)-4-chloro-2-methylpyridine (CAS 124736-64-7)
- Butylhydrazine Dihydrochloride (CAS 70629-61-7)
- (3R,4S)-3-aminotetrahydro-2H-pyran-4-ol (CAS 1638744-36-1)
- 2-Chloro-6-cyclopropoxy-N,N-dimethylaniline (CAS 1243472-18-5)
- N-(4-Chloro-3-ethyl-5-formylthiazol-2(3H)-ylidene)benzenesulfonamide (CAS 627471-09-4)
- (R)-(+)-1-(p-Tolyl)ethylamine (R)-(+)-4-(1-Aminoethyl)toluene 4187-38-6 T1380 (CAS 4187-38-6)
- 2,6-Dicyano-1-ethylpyridin-1-ium tetrafluoroborate (CAS 54387-66-5)
- 5-(5-Bromopyridin-3-yl)-3-(chloromethyl)-1,2,4-oxadiazole (CAS 1039335-76-6)
- Insulin Degludec Impurity 9 (CAS CATO-C4X-21579)
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