2-((3-Fluorobenzyl)sulfonyl)-1-methyl-4,5-diphenyl-1H-imidazole CAS 338957-03-2
| CAS No. | 338957-03-2 |
| Molecular Formula | C23H19FN2O2S |
| Molecular Weight | 406.47 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-((3-Fluorobenzyl)sulfonyl)-1-methyl-4,5-diphenyl-1H-imidazole.
2-((3-Fluorobenzyl)sulfonyl)-1-methyl-4,5-diphenyl-1H-imidazole (CAS 338957-03-2), molecular formula C23H19FN2O2S and molecular weight 406.47 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution, 2-((3-Fluorobenzyl)sulfonyl)-1-methyl-4,5-diphenyl-1H-imidazole is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 406.47 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C23H19FN2O2S |
| Molecular Weight | 406.47 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Fluorobenzyl Standards
- 2-((4-Fluorobenzyl)sulfonyl)-1-methyl-4,5-diphenyl-1H-imidazole (CAS 339277-77-9)
- 2-((5-((4-Fluorobenzyl)thio)-1,3,4-thiadiazol-2-yl)thio)-1-(4-methoxyphenyl)ethanone (CAS 477329-63-8)
- 5-((2-Fluorobenzyl)oxy)-2-(4-(3-methoxyphenoxy)-1H-pyrazol-3-yl)phenol (CAS 1009191-62-1)
- 3-(4-Ethyl-5-((4-fluorobenzyl)thio)-4H-1,2,4-triazol-3-yl)-1-phenylpyridazin-4(1H)-one (CAS 478063-61-5)
- 2-(4-Fluorobenzyl)-3-(4-methoxyphenyl)-1-oxo-1,2,3,4-tetrahydroisoquinoline-4-carboxylic acid (CAS 281205-72-9)
- 2-(4-(3-Fluorobenzyl)-3-oxo-3,4-dihydro-2H-benzo[b][1,4]oxazine-6-carbonyl)benzoic acid (CAS 439107-43-4)
- 2-((4-Fluorobenzyl)thio)-1-(4-fluorophenyl)-5-(4-methoxyphenyl)-1H-imidazole (CAS 1207001-23-7)
- 3-(5-((3-Fluorobenzyl)thio)-4-hexyl-4H-1,2,4-triazol-3-yl)-1H-indole (CAS 568560-96-3)
Recommended Standards
- 1-Benzyl 2-ethyl 5-((tert-butoxycarbonyl)amino)piperidine-1,2-dicarboxylate (CAS 2386925-92-2)
- 2-((3R,6S)-3,6-bis(benzamido)cyclohex-1-en-1-yl)-2-methylpropanoic acid (CAS 2053652-04-1)
- 1,1'-(Oxybis(4,1-phenylene))bis(2-phenylethan-1-one) (CAS 51930-25-7)
- 1,1'-((4-Methoxyphenyl)methylene)bis(naphthalen-2-ol) (CAS 66595-89-9)
- 32480-06-1 2-(~13~C)Methyl(1,3-~13~C_2_)propan-2-ol DTXSID10647768 (CAS 32480-06-1)
- 4-(2,6-Difluorophenyl)-5-methyl-2-(4-nitrobenzyl)-2,4-dihydro-3H-1,2,4-triazol-3-one (CAS 861206-33-9)
- 5-Methylfurmethiodide, 98% (CAS 1197-60-0)
- 1-(3-Bromophenyl)-2-(propylthio)ethan-1-one (CAS 1157363-95-5)
- 4-Methyl-2-thioxo-2,3-dihydrothiazole-5-carboxylic acid (CAS 57658-34-1)
- Methyl 2-(azetidin-2-yl)acetate (CAS 1391199-75-9)
- N-([1,3]Dioxolo[4',5':4,5]benzo[1,2-d]thiazol-6-yl)-2-bromobenzamide (CAS 892854-49-8)
- 4-[(3-methylpiperazin-1-yl)methyl]benzonitrile dihydrochloride (CAS 1461714-91-9)
- methyl 4-(4-bromo-2-fluorophenoxy)butanoate (CAS 1096852-55-9)
- Insulin Degludec Impurity 3 (CAS CATO-C4X-21573)
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