(2E)-2-(5-Amino-1,3,4-thiadiazol-2-yl)-3-(2-fluorophenyl)prop-2-enenitrile CAS 338959-97-0
| CAS No. | 338959-97-0 |
| Molecular Formula | C11H7FN4S |
| Molecular Weight | 246.26 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
(2E)-2-(5-Amino-1,3,4-thiadiazol-2-yl)-3-(2-fluorophenyl)prop-2-enenitrile (CAS 338959-97-0) is a high-purity analytical reference standard with the molecular formula C11H7FN4S and a molecular weight of 246.26 g/mol.
Owing to a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, fluorine substitution, (2E)-2-(5-Amino-1,3,4-thiadiazol-2-yl)-3-(2-fluorophenyl)prop-2-enenitrile is typically pale yellow to yellow low-melting solid. Its solid-state physicochemical attributes — including a molecular weight of 246.26 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C11H7FN4S |
| Molecular Weight | 246.26 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 4 |
| Sulfur Atoms | 1 |
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Recommended Standards
- (2,7-Dimethyl-4-oxo-3,4-dihydroquinazolin-6-yl)methyl acetate (CAS 838858-86-9)
- (2Z)-3-(3,4-Dimethoxyphenyl)-2-[(1E)-(methoxyimino)methyl]prop-2-enenitrile (CAS 339278-30-7)
- (1R,3R,8AS)-1-METHYL-3-PHENYLTETRAHYDRO-3H-OXAZOLO[3,4-A]PYRAZINE-5,8-DIONE (CAS 249611-05-0)
- (5-(Hydroxymethyl)-1-methyl-1H-pyrazol-3-yl)methyl benzoate (CAS 2450997-89-2)
- 1-Isopropyl-1H-imidazole-2-carboxylic acid (hydrochloride) (CAS 2137950-53-7)
- Trans, trans-2,6-nonadienal (CAS 17587-33-6)
- 2-methoxycyclopentan-1-amine (CAS 954582-89-9)
- N-(4-(Trifluoromethyl)phenyl)quinazolin-4-amine (CAS 849589-40-8)
- 5-Hydroxy-4-azaphenanthrene (CAS 33155-90-7)
- 2-Methoxy-5-nitrobenzo[d]oxazole (CAS 1806324-97-9)
- 2-(4-Cyclopropyl-4-methyl-2,5-dioxoimidazolidin-1-yl)acetic acid (CAS 956355-40-1)
- Fmoc-β-cyclohexyl-D-Ala-OH (CAS 144701-25-7)
- ((1S,3s)-3-amino-1-methylcyclobutyl)methanol (CAS 2231665-22-6)
- Semaglutide Impurity 183 (CAS 159541-28-3)
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