4-(2-Chloro-6-fluorophenyl)-4,7-dihydrofuro[3,4-b]pyridine-2,5(1H,3H)-dione CAS 338960-22-8
| CAS No. | 338960-22-8 |
| Molecular Formula | C13H9ClFNO3 |
| Molecular Weight | 281.67 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 4-(2-Chloro-6-fluorophenyl)-4,7-dihydrofuro[3,4-b]pyridine-2,5(1H,3H)-dione is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies 4-(2-Chloro-6-fluorophenyl)-4,7-dihydrofuro[3,4-b]pyridine-2,5(1H,3H)-dione (CAS 338960-22-8), a certified reference material (molecular formula C13H9ClFNO3, MW 281.67 g/mol) for analytical method development and quality control.
Structurally, 4-(2-Chloro-6-fluorophenyl)-4,7-dihydrofuro[3,4-b]pyridine-2,5(1H,3H)-dione (C13H9ClFNO3) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 9.0, corresponding to approximately 9 ring(s) or double-bond equivalent(s). With a molecular weight of 281.67 g/mol, it falls into the medium-molecular-weight range. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 4-(2-Chloro-6-fluorophenyl)-4,7-dihydrofuro[3,4-b]pyridine-2,5(1H,3H)-dione under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C13H9ClFNO3 |
| Molecular Weight | 281.67 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
Related Chloro Standards
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Recommended Standards
- 1-(Benzyloxy)-3-chloro-2-fluoro-5-nitrobenzene (CAS 1881320-57-5)
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- Lapatinib Impurity 28 (CAS 443882-99-3)
- 1-(Benzyloxy)-2-chloro-4-fluoro-3-nitrobenzene (CAS 1881291-26-4)
- N-(4-Methylbenzyl)prop-2-yn-1-amine (CAS 892594-94-4)
- 4-(2-Ethylfuran-3-yl)benzene-1,2-diamine (CAS 471239-83-5)
- Benzyltriethylammonium Borohydride (CAS 85874-45-9)
- 2-Methyl-5,6-dihydro-4H-pyrrolo[3,4-d]thiazole dihydrobromide (CAS 2060006-12-2)
- N-(4-Hydroxybutyl)-1,3-dimethyl-2,4-dioxo-1,2,3,4-tetrahydrothieno[2,3-d]pyrimidine-6-carboxamide (CAS 946207-13-2)
- 1-Cyanoindolizine-2-carboxylic acid (CAS 852562-13-1)
- Apatinib Impurity 5 (CAS CATO-C4X-29365)
- 4-(4-Methoxybenzoyl)-1H-pyrrole-2-carboxylic acid (CAS 886361-13-3)
- Tert-butyl (2-(4-chlorophenyl)-2-hydroxyethyl)carbamate (CAS 939757-24-1)
- Semaglutide impurity 83 (CAS CATO-C4X-222683)
Why CATO?
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