4-[(Benzenesulfonyl)methyl]-6-[(4-bromophenyl)sulfanyl]-2-methylpyrimidine CAS 338960-48-8
| CAS No. | 338960-48-8 |
| Molecular Formula | C18H15BrN2O2S2 |
| Molecular Weight | 435.36 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 4-[(Benzenesulfonyl)methyl]-6-[(4-bromophenyl)sulfanyl]-2-methylpyrimidine.
CATO supplies 4-[(Benzenesulfonyl)methyl]-6-[(4-bromophenyl)sulfanyl]-2-methylpyrimidine (CAS 338960-48-8), a certified reference material (molecular formula C18H15BrN2O2S2, MW 435.36 g/mol) for analytical method development and quality control.
The molecular framework of 4-[(Benzenesulfonyl)methyl]-6-[(4-bromophenyl)sulfanyl]-2-methylpyrimidine (C18H15BrN2O2S2) is characterized by a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, bromine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 4-[(Benzenesulfonyl)methyl]-6-[(4-bromophenyl)sulfanyl]-2-methylpyrimidine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C18H15BrN2O2S2 |
| Molecular Weight | 435.36 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 2 |
Related Benzenesulfonyl Standards
- 1027069-88-0 1-(Benzenesulfonyl)-4-bromo-1H-indole-3-sulfonyl chloride DTXSID30673963 (CAS 1027069-88-0)
- 5-(Benzenesulfonyl)-4-[(3-methoxyphenyl)sulfanyl]-2-phenylpyrimidine (CAS 478080-94-3)
- 3-(Benzenesulfonyl)-4,6-dimethylpyridin-2-yl 2,6-dichlorobenzoate (CAS 400082-21-5)
- 7-(benzenesulfonyl)-4-chloro-6-iodo-7H-pyrrolo[2,3-d]pyrimidine (CAS 876343-09-8)
- 3-(Benzenesulfonyl)-5-(3-methoxyphenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine (CAS 685108-20-7)
- 1-Benzenesulfonyl-5-chloro-3-iodo-1H-pyrrolo[2,3-b]pyridine (CAS 1001414-09-0)
- 4-[1-(Benzenesulfonyl)ethyl]-5-ethyl-1-{[3-(trifluoromethyl)phenyl]methyl}-2,3-dihydro-1H-imidazol-2-one (CAS 439096-16-9)
- 3-(Benzenesulfonyl)-4-methyl-2-[(4-methylphenyl)sulfanyl]-6-phenylpyridine (CAS 343372-77-0)
Recommended Standards
- 4-[(4-Bromophenyl)sulfanyl]-6-(methanesulfonylmethyl)-2-phenylpyrimidine (CAS 338967-63-8)
- Diethyl 1-(4-phenyl-6-(trifluoromethyl)pyrimidin-2-yl)-1H-1,2,3-triazole-4,5-dicarboxylate (CAS 861210-43-7)
- 2-((4-Allyl-5-(thiophen-2-yl)-4H-1,2,4-triazol-3-yl)thio)-N-(2-bromophenyl)acetamide (CAS 618879-89-3)
- Ethyl 2-(2,2,3,3,4,4,4-heptafluorobutanamido)-6-methyl-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxylate (CAS 300860-41-7)
- 3-(Benzo[d][1,3]dioxol-5-ylmethyl)-2-thioxothiazolidin-4-one (CAS 28824-73-9)
- N-Methyl-N-phenylnaphthalen-2-amine (CAS 6364-05-2)
- 2,3-Dimethyl-9H-carbazole (CAS 18992-70-6)
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- 2-Bromo-3-nitroquinoline (CAS 1378258-92-4)
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