9-(Thiophen-2-yl)-2,4-bis(trifluoromethyl)-[1,2,4]triazolo[4,3-a][1,8]naphthyridine CAS 338962-24-6
| CAS No. | 338962-24-6 |
| Molecular Formula | C15H6F6N4S |
| Molecular Weight | 388.29 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures 9-(Thiophen-2-yl)-2,4-bis(trifluoromethyl)-[1,2,4]triazolo[4,3-a][1,8]naphthyridine under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
9-(Thiophen-2-yl)-2,4-bis(trifluoromethyl)-[1,2,4]triazolo[4,3-a][1,8]naphthyridine (CAS 338962-24-6), molecular formula C15H6F6N4S and molecular weight 388.29 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 9-(Thiophen-2-yl)-2,4-bis(trifluoromethyl)-[1,2,4]triazolo[4,3-a][1,8]naphthyridine (C15H6F6N4S) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C15H6F6N4S |
| Molecular Weight | 388.29 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 4 |
| Sulfur Atoms | 1 |
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Recommended Standards
- 3-[(2,6-Dichlorophenyl)methyl]-1-[(4-methoxyphenyl)methyl]-2-methyl-1,4-dihydropyridin-4-one (CAS 339017-32-2)
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- 3-((2,6-Dichlorobenzyl)oxy)-2-methyl-1-(4-methylbenzyl)pyridin-4(1H)-one (CAS 338956-78-8)
- Pentafluorophenyl 2-(tetrahydro-2H-pyran-4-yloxy)benzoate (CAS 926921-58-6)
- 5-Chloro-3-(trifluoromethyl)picolinic acid (CAS 1198475-43-2)
- 8-Oxa-2-azaspiro[4.5]decan-3-one (CAS 194862-84-5)
- 5-(1-Ethylcyclohexyl)isoxazol-3-amine (CAS 81479-74-5)
- 959239-77-1 4-Chloro-2-methyl-5-propylpyrimidine DTXSID20650945 (CAS 959239-77-1)
- 2-((4-Fluorobenzyl)thio)acetonitrile (CAS 933673-53-1)
- Ethyl (E)-(2-cyano-3-(3,4-dichlorophenyl)acryloyl)carbamate (CAS 1215849-96-9)
- (2-(Cyclobutylamino)thiazol-4-yl)boronic acid (CAS 1310383-66-4)
- 4-((5-Bromo-2-(trifluoromethoxy)phenyl)sulfonyl)morpholine (CAS 1704065-46-2)
- m-PEG6-C6-phosphonic acid ethyl ester (CAS 2028281-88-9)
- D-[Phe]6-Semaglutide (CAS CATO-CPTD788633)
Why CATO?
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