2-{[(4-methylphenyl)methyl]sulfanyl}-4-(piperidin-1-yl)-5,6,7,8-tetrahydroquinazoline CAS 338963-55-6
| CAS No. | 338963-55-6 |
| Molecular Formula | C21H27N3S |
| Molecular Weight | 353.52 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-{[(4-methylphenyl)methyl]sulfanyl}-4-(piperidin-1-yl)-5,6,7,8-tetrahydroquinazoline.
CATO supplies 2-{[(4-methylphenyl)methyl]sulfanyl}-4-(piperidin-1-yl)-5,6,7,8-tetrahydroquinazoline (CAS 338963-55-6), a certified reference material (molecular formula C21H27N3S, MW 353.52 g/mol) for analytical method development and quality control.
The molecular framework of 2-{[(4-methylphenyl)methyl]sulfanyl}-4-(piperidin-1-yl)-5,6,7,8-tetrahydroquinazoline (C21H27N3S) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 2-{[(4-methylphenyl)methyl]sulfanyl}-4-(piperidin-1-yl)-5,6,7,8-tetrahydroquinazoline under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C21H27N3S |
| Molecular Weight | 353.52 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related methylphenyl Standards
- 2-{[bis(4-methylphenyl)-4h-1,2,4-triazol-3-yl]sulfanyl}acetohydrazide (CAS 893726-40-4)
- 5-(4-Methylphenyl)-2-(piperidin-1-yl)-[1,3]thiazolo[4,5-b]pyridine-7-carboxylic acid (CAS 852400-01-2)
- 1-(3-Methylphenyl)-5-(4-phenylphenyl)-1h-pyrazole-3-carboxylic acid (CAS 955964-50-8)
- 3-{1-[(4-methylphenyl)methyl]-5-oxopyrrolidine-3-amido}benzoic acid (CAS 1291859-15-8)
- 5-{[6-(4-Methylphenyl)imidazo[2,1-b][1,3]thiazol-5-yl]methylene}-2,4,6(1H,3H,5H)-pyrimidinetrione (CAS 861212-97-7)
- 5-[(4-Methylphenyl)sulfanyl]-3,6-diphenyl-1,2,4-triazine (CAS 339013-00-2)
- 2-{[(4-methylphenyl)methyl]sulfanyl}-4-(morpholin-4-yl)-5,6,7,8-tetrahydroquinazoline (CAS 338963-54-5)
- ((4-Methylphenyl)amino)(4-(3-phenylprop-2-enyl)piperazinyl)methane-1-thione (CAS 431912-08-2)
Recommended Standards
- 1-(4-Bromophenyl)-5-chloro-3-(trifluoromethyl)-1H-pyrazole-4-carbaldehyde (CAS 1152971-38-4)
- 5-(4-bromophenyl)-2-(trifluoromethyl)-3-furoyl chloride (CAS 231953-36-9)
- Allyl(chloropropyl)dichlorosilane (CAS 96550-26-4)
- 3-(Benzyloxy)-2-(3-((tert-butyldimethylsilyl)oxy)prop-1-yn-1-yl)pyridine (CAS 1228666-14-5)
- 28705-88-6 4-Hydroxychlorpropham Sulfate (CAS 28705-88-6)
- 2-(Phenyl-2-D)pyridine (CAS 372492-47-2)
- 595597-01-6 tert-Butyl (1,1-dioxo-1lambda~6~-thian-4-yl)carbamate DTXSID10718467 (CAS 595597-01-6)
- N-((3-(Aminomethyl)-1,2,4-oxadiazol-5-yl)methyl)cyclopropanecarboxamide (CAS 1706460-57-2)
- 4-Methoxy Meloxicam (CAS 1391051-96-9)
- 6-Chloro-5-isobutylpyrazine-2-carboxamide (CAS 182244-16-2)
- Methyl 2-(dimethylamino)pyridine-4-carboxylate (CAS 26156-52-5)
- 1,3-dimethyl-1H-pyrazolo[3,4-b]pyridine-6-carboxylic acid (CAS 1339529-36-0)
- tert-Butyl (1H-benzo[d]imidazol-2-yl)carbamate (CAS 77474-99-8)
- Semaglutide Impurity 129 (CAS 2490269-79-7)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com