2-(Phenylthio)-5-(3-(trifluoromethyl)phenyl)nicotinonitrile CAS 338964-69-5
| CAS No. | 338964-69-5 |
| Molecular Formula | C19H11F3N2S |
| Molecular Weight | 356.36 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 2-(Phenylthio)-5-(3-(trifluoromethyl)phenyl)nicotinonitrile is closely related to a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies 2-(Phenylthio)-5-(3-(trifluoromethyl)phenyl)nicotinonitrile (CAS 338964-69-5), a certified reference material (molecular formula C19H11F3N2S, MW 356.36 g/mol) for analytical method development and quality control.
2-(Phenylthio)-5-(3-(trifluoromethyl)phenyl)nicotinonitrile (C19H11F3N2S) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, fluorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 2-(Phenylthio)-5-(3-(trifluoromethyl)phenyl)nicotinonitrile under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C19H11F3N2S |
| Molecular Weight | 356.36 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Phenylthio Standards
- 1-((4-(Phenylthio)tetrahydro-2H-pyran-4-yl)methyl)-3-(o-tolyl)urea (CAS 1797727-02-6)
- 4-(Phenylthio)-N-(4-(pyridin-3-yl)thiazol-2-yl)butanamide (CAS 848298-36-2)
- 3-(Phenylthio)-N-(2-(3-(thiophen-2-yl)-1H-pyrazol-1-yl)ethyl)propanamide (CAS 1797014-56-2)
- 1'-(4-(Phenylthio)phenyl)-[1,3'-bipyrrolidine]-2',5'-dione (CAS 89143-19-1)
- 2-(2-(Phenylthio)acetamido)-5,6,7,8-tetrahydro-4H-cyclohepta[b]thiophene-3-carboxamide (CAS 895485-15-1)
- 3-Methyl 5-(2-(phenylthio)ethyl) 2,4,6-trimethyl-1,4-dihydropyridine-3,5-dicarboxylate (CAS 123875-01-4)
- 4-(2-Phenyl-6-((phenylthio)methyl)pyrimidin-4-yl)morpholine (CAS 303147-15-1)
- 4-(6-((Phenylthio)methyl)-2-(pyridin-4-yl)pyrimidin-4-yl)morpholine (CAS 303147-61-7)
Recommended Standards
- 2-((11,11-Dioxido-3H-benzo[5,6][1,4]oxathiino[3,2-e]indol-1-yl)methylene)hydrazine-1-carboxamide (CAS 371199-44-9)
- 2-{[(3-methoxyphenyl)methyl]sulfanyl}-3-(prop-2-en-1-yl)-6-(trifluoromethyl)-3,4-dihydropyrimidin-4-one (CAS 866143-20-6)
- 1-(4-Hydroxy-3,5-dimethylphenyl)-2-((3-(trifluoromethyl)phenyl)sulfinyl)ethan-1-one (CAS 344279-84-1)
- 2-{[5-(4-nitrophenyl)-4-phenyl-4H-1,2,4-triazol-3-yl]sulfanyl}acetic acid (CAS 790270-85-8)
- 2-Amino-1-(3,4-dichlorophenyl)-4,5-dimethyl-1H-pyrrole-3-carbonitrile (CAS 72578-55-3)
- 5-fluoro-1H-pyrazolo[3,4-b]pyridin-3-amine (CAS 1034667-22-5)
- 2-Chloro-5-(2-chloroethyl)thiazole (CAS 2803864-59-5)
- Leucronine Hydrate (CAS 138-60-3)
- 2-Chloro-N-(3-methylpyridin-2-yl)acetamide hydrochloride (CAS 1241719-79-8)
- 2,4,5-Trichlorobenzenethiol (CAS 3773-14-6)
- Dicamba sodiumsalt (CAS 1982-69-0)
- 5-(Pyridazin-4-yl)nicotinamide (CAS 1346687-47-5)
- Cyclopropyl(3,4-difluorophenyl)methanamine (CAS 535925-85-0)
- Semaglutide impurity 65 (CAS CATO-C4X-222665)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com