9-(2-Chloro-6-fluorophenyl)-6-(trifluoromethyl)-[1,2,4]triazolo[4,3-a]1,8-naphthyridine CAS 338968-41-5
| CAS No. | 338968-41-5 |
| Molecular Formula | C16H7ClF4N4 |
| Molecular Weight | 366.70 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 9-(2-Chloro-6-fluorophenyl)-6-(trifluoromethyl)-[1,2,4]triazolo[4,3-a]1,8-naphthyridine is closely related to a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
9-(2-Chloro-6-fluorophenyl)-6-(trifluoromethyl)-[1,2,4]triazolo[4,3-a]1,8-naphthyridine (CAS 338968-41-5) is a high-purity analytical reference standard with the molecular formula C16H7ClF4N4 and a molecular weight of 366.70 g/mol.
9-(2-Chloro-6-fluorophenyl)-6-(trifluoromethyl)-[1,2,4]triazolo[4,3-a]1,8-naphthyridine (C16H7ClF4N4) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 9-(2-Chloro-6-fluorophenyl)-6-(trifluoromethyl)-[1,2,4]triazolo[4,3-a]1,8-naphthyridine under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C16H7ClF4N4 |
| Molecular Weight | 366.70 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 4 |
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Recommended Standards
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- 2,6,10,14,18-Pentamethylheneicosane (CAS 66519-77-5)
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- Z-Leu-Tyr-NH2 (CAS 17263-42-2)
- 3-Chloro-N-methylbenzylamine (CAS 39191-07-6)
- 2-Chloro-N-methyl-N-(3-methylbenzyl)acetamide (CAS 39096-52-1)
- tert-butyl 3-amino-2,3-dihydro-1H-indene-1-carboxylate (CAS 1909308-65-1)
- 2-Chloro-3-fluoro-4-(methylthio)pyridine (CAS 1826110-14-8)
- 4-(Benzyloxy)-2-ethyl-1H-indole (CAS 39843-70-4)
- Lubiprostone Impurity 23 (CAS CATO-C4X-113623)
- Ethyl 2-(2-chloroacetamido)-5,5,7,7-tetramethyl-4H,5H,6H,7H-thieno[2,3-c]pyridine-3-carboxylate hydrochloride (CAS 1171150-66-5)
- 1-[(4-Chlorophenyl)methyl]-3-methyl-4-(4-methylphenyl)-4,5-dihydro-1H-1,2,4-triazol-5-one (CAS 860651-03-2)
- Fibronectin Adhesion-Promoting Peptide (CAS 125720-21-0)
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