4-{[(4-chlorophenyl)amino]methylidene}-3-phenyl-4,5-dihydro-1H-pyrazol-5-one CAS 338975-62-5

Purity 97%+In StockPharmaceutical Standards
CAS No.338975-62-5
Molecular FormulaC16H12ClN3O
Molecular Weight297.74 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

4-{[(4-chlorophenyl)amino]methylidene}-3-phenyl-4,5-dihydro-1H-pyrazol-5-one CAS 338975-62-5 chemical structure

Description

CATO manufactures 4-{[(4-chlorophenyl)amino]methylidene}-3-phenyl-4,5-dihydro-1H-pyrazol-5-one under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

4-{[(4-chlorophenyl)amino]methylidene}-3-phenyl-4,5-dihydro-1H-pyrazol-5-one (CAS 338975-62-5), molecular formula C16H12ClN3O and molecular weight 297.74 g/mol, is a CATO reference standard with documented purity and traceability.

The molecular framework of 4-{[(4-chlorophenyl)amino]methylidene}-3-phenyl-4,5-dihydro-1H-pyrazol-5-one (C16H12ClN3O) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

Physical & Chemical Properties

Molecular FormulaC16H12ClN3O
Molecular Weight297.74 g/mol
AppearancePale yellow to yellow crystalline powder. (slight halide-like odor)
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)12.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)2025
Halogen ContentCl-containing
Nitrogen Atoms3

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