3-(2,4-dichlorophenyl)-5-piperidino[1,2,4]triazolo[4,3-c]quinazoline CAS 338977-92-7
| CAS No. | 338977-92-7 |
| Molecular Formula | C20H17Cl2N5 |
| Molecular Weight | 398.29 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 3-(2,4-dichlorophenyl)-5-piperidino[1,2,4]triazolo[4,3-c]quinazoline (C20H17Cl2N5) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
3-(2,4-dichlorophenyl)-5-piperidino[1,2,4]triazolo[4,3-c]quinazoline (CAS 338977-92-7), molecular formula C20H17Cl2N5 and molecular weight 398.29 g/mol, is a CATO reference standard with documented purity and traceability.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C20H17Cl2N5 |
| Molecular Weight | 398.29 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 5 |
Related dichlorophenyl Standards
- 3-(3,4-Dichlorophenyl)-5-(piperidin-1-yl)-[1,2,4]triazolo[4,3-c]quinazoline (CAS 338977-96-1)
- 5-{1-[(3,4-dichlorophenyl)methyl]-5,6-dimethyl-1H-1,3-benzodiazol-2-yl}-1,2-dihydropyridin-2-one (CAS 400077-30-7)
- N-(2,4-dichlorophenyl)-2-(2-(4-ethylphenoxy)acetyl)hydrazine-1-carbothioamide (CAS 889593-61-7)
- 2-(5-(2,4-Dichlorophenyl)furan-2-yl)-6-methylquinoline-4-carboxylic acid (CAS 634177-79-0)
- 3-(2,6-Dichlorophenyl)-5-methyl-N-(quinolin-8-yl)-1,2-oxazole-4-carboxamide (CAS 946386-97-6)
- 1-(2,4-Dichlorophenyl)-3-[2-methyl-4-(trifluoromethyl)-1,3-thiazole-5-carbonyl]urea (CAS 320420-62-0)
- 2-(3,4-Dichlorophenyl)-5-(furan-2-yl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine (CAS 439095-81-5)
- 2,4-Dichlorophenyl Isothiocyanate (CAS 6590-96-1)
Recommended Standards
- 3-(1-(3,4-Dichlorobenzyl)-5,6-dimethyl-1H-benzo[d]imidazol-2-yl)pyridin-2(1H)-one (CAS 860787-81-1)
- 3-(1-(2,6-Dichlorobenzyl)-5,6-dimethyl-1H-benzo[d]imidazol-2-yl)pyridin-2(1H)-one (CAS 860787-67-3)
- 3-(3-Bromobenzyl)-1-(tert-butoxycarbonyl)piperidine-3-carboxylic acid (CAS 959236-03-4)
- 2-(2-(4-Nitrophenoxy)acetyl)-N-(3-(trifluoromethyl)phenyl)hydrazine-1-carboxamide (CAS 905371-34-8)
- 2-Cyano-N-(1-phenylethyl)acetamide (CAS 59749-84-7)
- 1-{[1,1'-biphenyl]-4-yl}-2-[(5-phenyl-1,3,4-oxadiazol-2-yl)sulfanyl]ethan-1-one (CAS 477846-71-2)
- Methyl({[4-(2,2,2-trifluoroethoxy)phenyl]methyl})amine (CAS 1095157-60-0)
- 2-[cyclopentyl(methyl)amino]-5-fluorobenzaldehyde (CAS 1096809-50-5)
- 5-[3-fluoro-5-(trifluoromethyl)phenyl]-2H-1,2,3,4-tetrazole (CAS 874784-07-3)
- 4-Benzyl-1-(2,2-dimethyltetrahydro-2H-thiopyran-4-yl)-3-phenyl-1H-pyrazol-5(4H)-one (CAS 102689-18-9)
- 5-Methyl-1,1,1-trifluorohexane-2,4-dione (CAS 30984-28-2)
- (E)-{2-[(4-chlorophenyl)sulfanyl]-2-methylpropylidene}(methoxy)amine (CAS 306979-71-5)
- 2-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-6-(trifluoromethyl)pyridine (CAS 881402-16-0)
- Acetyl tetrapeptide-9(Dermican LS 9837) (CAS 928006-50-2)
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