Methyl 3,3,3-trifluoro-2-methylpropanoate CAS 339-17-3
| CAS No. | 339-17-3 |
| Molecular Formula | C5H7F3O2 |
| Molecular Weight | 156.10 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Methyl 3,3,3-trifluoro-2-methylpropanoate is closely related to a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies Methyl 3,3,3-trifluoro-2-methylpropanoate (CAS 339-17-3), a certified reference material (molecular formula C5H7F3O2, MW 156.10 g/mol) for analytical method development and quality control.
The molecular framework of Methyl 3,3,3-trifluoro-2-methylpropanoate (C5H7F3O2) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), Methyl 3,3,3-trifluoro-2-methylpropanoate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C5H7F3O2 |
| Molecular Weight | 156.10 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 1.0 |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | F-containing |
Related Methyl Standards
- (S)-4,4,4-Trifluoro-3-methylbutanoic acid (CAS 1009079-95-1)
- 1,1,1-Trifluoro-5-hydroxypentan-2-one (CAS 121749-66-4)
- 1,1,1-trifluoro-4-methoxy-butan-2-one (CAS 1410416-85-1)
- (2S)-4,4,4-Trifluoro-2-methylbutanoic acid (CAS 868666-12-0)
- (3S)-4,4,4-Trifluoro-3-hydroxy-3-methyl-2-butanone (CAS 2877757-07-6)
- (R)-4,4,4-Trifluoro-2-methylbutanoic acid (CAS 821775-25-1)
- (R)-4,4,4-Trifluoro-3-hydroxy-3-methylbutan-2-one (CAS 2875067-31-3)
- (R)-4,4,4-Trifluoro-3-methylbutanoic acid (CAS 835629-56-6)
Recommended Standards
- Ethyl 3,3,3-Trifluoropropanoate (CAS 352-23-8)
- n-propyl trifluoroacetate Impurity (CAS 383-66-4)
- Dihydroxy-1,2,4-triazine-6-carboxamide (CAS 89032-88-2)
- 2365-82-4 4,4,4-trifluoro-2-methylbutanoate 4,4,4-tris(fluoranyl)-2-methyl-butanoate A816827 (CAS 2365-82-4)
- 4-Methoxy-5-methyl-2-(piperidin-1-ylmethyl)thieno[2,3-d]pyrimidine-6-carboxylic acid (CAS 877826-27-2)
- 4-Methylsulfonylphenylisothiocyanate (CAS 15863-56-6)
- N-(2-Bromophenyl)-2-((3-ethyl-4-oxo-3,4,5,6,7,8-hexahydrobenzo[4,5]thieno[2,3-d]pyrimidin-2-yl)thio)acetamide (CAS 577960-68-0)
- 2-Methyl-5-((tetrahydro-2H-pyran-2-yl)oxy)benzaldehyde (CAS 2768872-23-5)
- Cyclopentanecarbohydrazide (CAS 3400-07-5)
- 2-(3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)propanenitrile (CAS 2366279-09-4)
- Ethyl 5,6,7,8-tetrahydro-1,6-naphthyridine-2-carboxylate (CAS 1256795-17-1)
- 4-Iodopyridine-2,6-dicarbaldehyde (CAS 506423-88-7)
- Salbutamol Impurity 99 (CAS 27475-09-8)
- Peptide Impurity 09 X TFA Salt (CAS CATO-CPTD788809)
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