2-(4-Chlorophenyl)-5-(4-fluorobenzoyl)-1,3-thiazole CAS 339008-18-3

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-(4-Chlorophenyl)-5-(4-fluorobenzoyl)-1,3-thiazole.

2-(4-Chlorophenyl)-5-(4-fluorobenzoyl)-1,3-thiazole (CAS 339008-18-3), molecular formula C16H9ClFNOS and molecular weight 317.77 g/mol, is a CATO reference standard with documented purity and traceability.

2-(4-Chlorophenyl)-5-(4-fluorobenzoyl)-1,3-thiazole (C16H9ClFNOS) contains a nitrogen-containing heterocyclic scaffold, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 2-(4-Chlorophenyl)-5-(4-fluorobenzoyl)-1,3-thiazole meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

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