1-(2,6-Dichlorobenzyl)-5-(pyrrolidine-1-carbonyl)pyridin-2(1H)-one CAS 339008-76-3
| CAS No. | 339008-76-3 |
| Molecular Formula | C17H16Cl2N2O2 |
| Molecular Weight | 351.23 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
1-(2,6-Dichlorobenzyl)-5-(pyrrolidine-1-carbonyl)pyridin-2(1H)-one (CAS 339008-76-3) is a high-purity analytical reference standard with the molecular formula C17H16Cl2N2O2 and a molecular weight of 351.23 g/mol.
1-(2,6-Dichlorobenzyl)-5-(pyrrolidine-1-carbonyl)pyridin-2(1H)-one (C17H16Cl2N2O2) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C17H16Cl2N2O2 |
| Molecular Weight | 351.23 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Dichlorobenzyl Standards
- 5-(2-(2,6-Dichlorobenzyl)pyrimidin-4-yl)-4-methylthiazol-2-amine (CAS 1163706-69-1)
- 2-((2,4-Dichlorobenzyl)thio)-5-(p-tolyl)-1,3,4-oxadiazole (CAS 332869-51-9)
- 5-Acetyl-2-((3,4-dichlorobenzyl)thio)-6-methylnicotinonitrile (CAS 328282-10-6)
- 5-((3,4-Dichlorobenzyl)oxy)-2-methylbenzofuran-3-carboxylic acid (CAS 307552-41-6)
- 1-(2,4-Dichlorobenzyl)-5-nitroindoline-2,3-dione (CAS 303149-87-3)
- 1-(2,6-Dichlorobenzyl)-3-methoxy-5-(trifluoromethyl)pyridin-2(1H)-one (CAS 339024-84-9)
- 3-(2,4-Dichlorobenzyl)-4-hydroxy-1-(2,2,2-trifluoroethyl)pyridin-2(1H)-one (CAS 478045-95-3)
- 1-[(2,6-Dichlorobenzyl)sulfonyl]piperidine-4-carboxylic acid (CAS 1858241-39-0)
Recommended Standards
- 1-(2-(2,6-Dichlorophenyl)-1-hydroxyethyl)-2-phenylpyrazolidin-3-one (CAS 60260-70-0)
- 2-(2,6-Dichlorophenoxy)-N-(4-oxo-2-thioxothiazolidin-3-yl)acetamide (CAS 866154-59-8)
- N-(1-methyl-7-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indazol-3-yl)methanesulfonamide (CAS 1620056-85-0)
- 2,4-Dichloro-N-(4-morpholinophenyl)benzamide (CAS 250714-46-6)
- tert-Butyl 3-Amino-4-hydroxypiperidine-1-carboxylate (CAS 454709-92-3)
- 2-(((4-Hydroxyphenyl)imino)methyl)quinolin-8-ol (CAS 5603-23-6)
- 2-(4-Bromo-2-fluorophenoxy)benzaldehyde (CAS 338393-63-8)
- 2,5-Dichloro-4-hydroxypyridine (CAS 847664-65-7)
- 5-Chloro-1H-pyrrolo[2,3-c]pyridine-7-carboxylic acid (CAS 2641485-07-4)
- (3-Fluoro-4-methylphenyl)hydrazine hydrochloride (CAS 156941-64-9)
- Apixaban Impurity 177 (CAS CATO-C4X-1088177)
- 3-(Heptafluorooctyl)aniline (CAS 119489-67-7)
- 4-chloro-3-fluoro-2-(morpholin-4-yl)aniline (CAS 1803603-63-5)
- Des-Asp15-Tirzepatide (CAS CATO-CPTD788958)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com