(4E)-4-{[(4-methylpyrimidin-2-yl)amino]methylidene}-2-phenyl-4,5-dihydro-1,3-oxazol-5-one CAS 339010-31-0
| CAS No. | 339010-31-0 |
| Molecular Formula | C15H12N4O2 |
| Molecular Weight | 280.28 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including (4E)-4-{[(4-methylpyrimidin-2-yl)amino]methylidene}-2-phenyl-4,5-dihydro-1,3-oxazol-5-one.
(4E)-4-{[(4-methylpyrimidin-2-yl)amino]methylidene}-2-phenyl-4,5-dihydro-1,3-oxazol-5-one (CAS 339010-31-0) is a high-purity analytical reference standard with the molecular formula C15H12N4O2 and a molecular weight of 280.28 g/mol.
The molecular framework of (4E)-4-{[(4-methylpyrimidin-2-yl)amino]methylidene}-2-phenyl-4,5-dihydro-1,3-oxazol-5-one (C15H12N4O2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), (4E)-4-{[(4-methylpyrimidin-2-yl)amino]methylidene}-2-phenyl-4,5-dihydro-1,3-oxazol-5-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C15H12N4O2 |
| Molecular Weight | 280.28 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Nitrogen Atoms | 4 |
Related E Standards
- 4-{[(5-methylpyrimidin-2-yl)sulfanyl]methyl}benzohydrazide (CAS 1273571-22-4)
- 4-{[(4-methylpyrimidin-2-yl)sulfanyl]methyl}benzohydrazide (CAS 1274854-13-5)
- 1-[4-(2-Methylpyrimidin-4-yl)phenyl]-1H-1,3-benzodiazole (CAS 439108-63-1)
- 3-(2-Methylpyrimidin-4-yl)benzenesulfonyl chloride (CAS 465514-07-2)
- N-(4-methylpyrimidin-2-yl)-4-nitrobenzene-1-sulfonamide (CAS 439928-67-3)
- 1-(4-Methylpyrimidin-2-yl)-3-(3-(trifluoromethyl)phenyl)urea (CAS 853318-49-7)
- 1,4-Bis(2-methylpyrimidin-5-yl)benzene (CAS 193886-29-2)
- 2-(((2-Methylpyrimidin-5-yl)methyl)amino)-5-nitropyrimidin-4(1H)-one (CAS 77961-32-1)
Recommended Standards
- (3-(((Benzyloxy)carbonyl)amino)propanoyl)glycine (CAS 58171-88-3)
- (R)-Methyl 4-nitro-3-(((tetrahydrofuran-2-yl)methyl)amino)benzoate (CAS 2704561-61-3)
- (2R,3S)-5-(2-amino-4-methoxy-1H-pyrrolo[2,3-d]pyrimidin-5-yl)-2-(hydroxymethyl)tetrahydrofuran-3-ol (CAS 86392-74-7)
- (S)-Methyl 3-(1H-imidazol-4-yl)-2-((S)-5-oxopyrrolidine-2-carboxamido)propanoate (CAS 25575-88-6)
- 2-(3-oxocyclobutyl)acetonitrile (CAS 2007916-61-0)
- (2s)-7-Hydroxy-3'-methylspiro[chromane-2,1'-cyclohexan]-4-one (CAS 1242843-10-2)
- [(3-Methylphenyl)methyl](2-methylpropyl)amine (CAS 1019606-15-5)
- 4-(fluoromethyl)tetrahydrofuran-2-one (CAS 813452-00-5)
- 2-((2-Nitrobenzyl)amino)acetic acid (CAS 42749-52-0)
- 2-Chloro-N-(3-cyanobenzyl)-N-isopropylacetamide (CAS 1353976-30-3)
- H-AEEA-OH HCl (CAS 134979-01-4)
- Ondansetron-13C-d3 (CAS CATO-C4X-139419)
- 7-Methoxy-1-methyl-5-phenyl-1H-indol-4-yl acetate (CAS 99497-21-9)
- Pancreatic Polypeptide (human) trifluoroacetate salt (CAS 75976-10-2)
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