2-Tosyl-N-(5-(trifluoromethyl)-1,3,4-thiadiazol-2-yl)acetamide CAS 339014-06-1
| CAS No. | 339014-06-1 |
| Molecular Formula | C12H10F3N3O3S2 |
| Molecular Weight | 365.35 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-Tosyl-N-(5-(trifluoromethyl)-1,3,4-thiadiazol-2-yl)acetamide.
2-Tosyl-N-(5-(trifluoromethyl)-1,3,4-thiadiazol-2-yl)acetamide (CAS 339014-06-1) is a high-purity analytical reference standard with the molecular formula C12H10F3N3O3S2 and a molecular weight of 365.35 g/mol.
The molecular framework of 2-Tosyl-N-(5-(trifluoromethyl)-1,3,4-thiadiazol-2-yl)acetamide (C12H10F3N3O3S2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 2-Tosyl-N-(5-(trifluoromethyl)-1,3,4-thiadiazol-2-yl)acetamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H10F3N3O3S2 |
| Molecular Weight | 365.35 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 2 |
Related Tosyl Standards
- 3-Phenyl-4-tosyl-3,4-dihydro-2H-benzo[b][1,4]oxazine (CAS 478048-63-4)
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- Ethyl 4-tosyl-3,4-dihydro-2H-benzo[b][1,4]oxazine-2-carboxylate (CAS 35017-54-0)
- 7'-Methyl-2'-tosyl-2',3'-dihydro-1'H-spiro[cyclohexane-1,4'-isoquinoline] (CAS 1425335-80-3)
- 1-Tosyl-1H-indole-3-sulfonyl chloride (CAS 881406-30-0)
- 5-Tosyl-5,6-dihydroindolo[2,3-b]indole (CAS 1607470-19-8)
- 1-(1-Tosyl-1H-benzo[d]imidazol-2-yl)piperidin-3-ol (CAS 1146080-28-5)
- 1-Benzyl-6-tosyl-1,6-diazaspiro[3.3]Heptan-3-ol (CAS 1349199-70-7)
Recommended Standards
- 2-Phenoxy-3-[3-(trifluoromethyl)phenyl]quinoline (CAS 337921-83-2)
- 4,4,6-Trimethyl-1,2-dioxo-1,2-dihydro-4H-pyrrolo[3,2,1-ij]quinolin-8-yl 3-fluorobenzoate (CAS 727664-64-4)
- 2-Oxo-2-((3-(trifluoromethyl)phenyl)amino)ethyl 2-phenylbutanoate (CAS 380175-32-6)
- 5-[4-(3-Methoxyphenyl)piperazin-1-yl]-1-methyl-3-(trifluoromethyl)-1H-pyrazole-4-carbonitrile (CAS 324009-10-1)
- 2-Chloro-1-(2-((dimethylamino)methyl)piperidin-1-yl)ethanone (CAS 1353956-44-1)
- N-MEthyl-6-piperidin-3-ylnicotinamide dihydrochloride (CAS 1858255-34-1)
- 4-Fluoro-2H,3H-furo[2,3-b]pyridine (CAS 1818847-50-5)
- 4-(Difluoromethyl)-5-(hydroxymethyl)-6-methylpyridin-3-ol (CAS 1806976-78-2)
- (5-Fluoro-2-morpholinophenyl)methanamine (CAS 905439-34-1)
- 2-(Tert-butyl)-4,6-dichloro-5-ethylpyrimidine (CAS 1341681-83-1)
- 2-Ethyl-1H-imidazo[4,5-f]quinoxaline (CAS 122228-79-9)
- 7-Chloro-1-(4-(trifluoromethoxy)phenyl)heptan-1-one (CAS 898786-10-2)
- (2S)-N-(2,2-dimethylthietan-3-yl)-2-hydroxypropanamide (CAS 1849167-01-6)
- Semaglutide Impurity 184 (CAS CATO-C4X-2226184)
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