2,6-Difluoro-N-(2-hydroxy-2-(naphthalen-2-yl)ethyl)benzamide CAS 339014-44-7
| CAS No. | 339014-44-7 |
| Molecular Formula | C19H15F2NO2 |
| Molecular Weight | 327.32 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 327.32 g/mol gives 2,6-Difluoro-N-(2-hydroxy-2-(naphthalen-2-yl)ethyl)benzamide distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
2,6-Difluoro-N-(2-hydroxy-2-(naphthalen-2-yl)ethyl)benzamide (CAS 339014-44-7), molecular formula C19H15F2NO2 and molecular weight 327.32 g/mol, is a CATO reference standard with documented purity and traceability.
2,6-Difluoro-N-(2-hydroxy-2-(naphthalen-2-yl)ethyl)benzamide (C19H15F2NO2) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C19H15F2NO2 |
| Molecular Weight | 327.32 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
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Recommended Standards
- 1,3-Bis[(4-fluorophenyl)methyl]-4-hydroxy-1,2-dihydropyridin-2-one (CAS 478247-88-0)
- 2-[(4,6-Dimethylpyrimidin-2-yl)sulfanyl]-N-(2,4,5-trifluorophenyl)acetamide (CAS 303091-38-5)
- (3S,4R)-1-(tert-butoxycarbonyl)-4-(2,4-difluorophenyl)pyrrolidine-3-carboxylic acid (CAS 862282-35-7)
- 3-(3-(3-(1,1,2,2-Tetrafluoroethoxy)phenyl)propyl)aniline (CAS 89807-71-6)
- 2-cyclobutylideneacetaldehyde (CAS 97592-29-5)
- 4-Chloro-2-methyl-1H-indole-5-carboxylic acid (CAS 1507880-53-6)
- (2S,3R,4S,5S)-5-((R)-1-hydroxy-2-(pivaloyloxy)ethyl)tetrahydrofuran-2,3,4-triyl tris(2,2-dimethylpropanoate) (CAS 226877-02-7)
- [1-(2-phenylethyl)-1h-pyrazol-4-yl]methanol (CAS 1341611-65-1)
- 1-(2,2-Difluoroethyl)-N-(thiophen-2-ylmethyl)-1H-pyrazol-4-amine hydrochloride (CAS 1856067-64-5)
- Hexadecyltriphenylphosphonium bromide (CAS 14866-43-4)
- 4-(3-Chloroisoquinolin-1-yl)morpholine (CAS 60691-01-2)
- (7-Nitro-2,3-dihydrobenzo[b][1,4]dioxin-6-yl)(p-tolyl)methanone (CAS 634172-65-9)
- 3-[(3-Bromobenzyl)oxy]benzaldehyde (CAS 137489-76-0)
- Tau Peptide (301-315) trifluoroacetate salt (CAS 330456-48-9)
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