N-(2,4-Dichloro-5-methoxyphenyl)-3-(2-nitrophenoxy)thiophene-2-carboxamide CAS 339015-20-2
| CAS No. | 339015-20-2 |
| Molecular Formula | C18H12Cl2N2O5S |
| Molecular Weight | 439.27 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
N-(2,4-Dichloro-5-methoxyphenyl)-3-(2-nitrophenoxy)thiophene-2-carboxamide (CAS 339015-20-2), molecular formula C18H12Cl2N2O5S and molecular weight 439.27 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of N-(2,4-Dichloro-5-methoxyphenyl)-3-(2-nitrophenoxy)thiophene-2-carboxamide (C18H12Cl2N2O5S) is characterized by a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
As a certified reference material (CRM), N-(2,4-Dichloro-5-methoxyphenyl)-3-(2-nitrophenoxy)thiophene-2-carboxamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C18H12Cl2N2O5S |
| Molecular Weight | 439.27 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related N Standards
- N-(2,4-dichloro-5-methoxyphenyl)-3-(4-nitrophenoxy)thiophene-2-carboxamide (CAS 339015-25-7)
- 7,9-Dichloro-2-(4-methoxyphenyl)-5-(p-tolyl)-5,10b-dihydro-1H-benzo[e]pyrazolo[1,5-c][1,3]oxazine (CAS 303061-34-9)
- 2-({[2,4-dichloro-5-(2-methoxyethoxy)phenyl]carbamoyl}methanesulfinyl)-N,N-diethylacetamide (CAS 341965-08-0)
- 2,4-Dichloro-N'-{2',3'-dihydrospiro[adamantane-2,1'-indene]-3'-ylidene}benzohydrazide (CAS 400083-54-7)
- 3-(5,6-Dichloro-1-(2,4-dichlorobenzyl)-1H-benzo[d]imidazol-2-yl)pyridin-2(1H)-one (CAS 338412-08-1)
- 3-(5,6-Dichloro-1-(2,6-dichlorobenzyl)-1H-benzo[d]imidazol-2-yl)pyridin-2(1H)-one (CAS 338774-41-7)
- 3-{5,6-dichloro-1-[(3,4-dichlorophenyl)methyl]-1H-1,3-benzodiazol-2-yl}-1,2-dihydropyridin-2-one (CAS 338774-14-4)
- 5-{5,6-dichloro-1-[(2,4-dichlorophenyl)methyl]-1H-1,3-benzodiazol-2-yl}-1,2-dihydropyridin-2-one (CAS 338773-97-0)
Recommended Standards
- 2-(4-(2-Fluorophenyl)piperazin-1-yl)-N-(4-iodophenyl)acetamide (CAS 328287-39-4)
- Tert-butyl (S)-4-(4-iodobenzyl)-1,2,3-oxathiazolidine-3-carboxylate 2,2-dioxide (CAS 1823597-92-7)
- Sofosbuvir Impurity 96 (CAS 1392015-05-2)
- N-((5-Bromothiophen-2-yl)methyl)-1-(3,4-difluorobenzyl)-2-oxo-1,2-dihydropyridine-3-carboxamide (CAS 1001413-88-2)
- 2-(4-Hydroxy-2-oxoindolin-3-yl)acetonitrile (CAS 1380540-77-1)
- 2-(Difluoromethyl)-3,5-dimethylpyridine (CAS 1804445-64-4)
- (S)-Pent-4-yn-2-ol (CAS 81939-73-3)
- 2-{[1-butyl-5-(trifluoromethyl)-1h-1,3-benzodiazol-2-yl]sulfanyl}acetic acid (CAS 868238-03-3)
- (S)-tert-Butyl (1-(oxazol-5-yl)ethyl)carbamate (CAS 196819-41-7)
- N-(3-Methoxy-4-(oxazol-5-yl)phenyl)-2-phenylacetamide (CAS 267405-93-6)
- Prusogliptin Impurity 9 (CAS CATO-C4X-32849)
- (2-Fluorospiro[3.3]heptan-2-yl)methanol (CAS 2408972-91-6)
- Diphenyl[4-(4-Fluorophenyl)-6-isopropyl-2-(N-methylmethylsulfonyl)amino-pyrimidin-5-yl-methyl]phosphine Oxide-d6 (CAS 1185122-39-7)
- Semaglutide impurity 29 (CAS 1188328-22-4)
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