N-(2,4-dichloro-5-isopropoxyphenyl)-3-(4-nitrophenoxy)thiophene-2-carboxamide CAS 339015-26-8
| CAS No. | 339015-26-8 |
| Molecular Formula | C20H16Cl2N2O5S |
| Molecular Weight | 467.32 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including N-(2,4-dichloro-5-isopropoxyphenyl)-3-(4-nitrophenoxy)thiophene-2-carboxamide.
N-(2,4-dichloro-5-isopropoxyphenyl)-3-(4-nitrophenoxy)thiophene-2-carboxamide (CAS 339015-26-8) is a high-purity analytical reference standard with the molecular formula C20H16Cl2N2O5S and a molecular weight of 467.32 g/mol.
The molecular framework of N-(2,4-dichloro-5-isopropoxyphenyl)-3-(4-nitrophenoxy)thiophene-2-carboxamide (C20H16Cl2N2O5S) is characterized by a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C20H16Cl2N2O5S |
| Molecular Weight | 467.32 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related N Standards
- N-(2,4-dichloro-5-isopropoxyphenyl)-3-(2-nitrophenoxy)thiophene-2-carboxamide (CAS 339015-21-3)
- 3,4-Dichloro-N-(3-cyano-4-{[3-(trifluoromethyl)phenyl]sulfanyl}phenyl)benzamide (CAS 477866-66-3)
- N-(2,4-Dichloro-5-methoxyphenyl)-2-[({[3-(trifluoromethyl)phenyl]carbamoyl}methyl)sulfanyl]acetamide (CAS 341965-12-6)
- Dichloro[8-(di-tert-butylphosphinooxy)quinoline]palladium(II) (CAS 1100332-45-3)
- 4,6-Dichloro-1-nitroanthracene-9,10-dione (CAS 60506-83-4)
- 2,4-Dichloro-5-iodo-7-tosyl-7H-pyrrolo[2,3-d]pyrimidine (CAS 1116240-01-7)
- Methyl 5,7-dichloro-4-(3,3-diphenylureido)quinoline-2-carboxylate (CAS 210692-60-7)
- (E)-{1-[2,3-dichloro-4-(ethanesulfonyl)phenyl]-2-(4-fluorobenzenesulfonyl)ethylidene}(methoxy)amine (CAS 861208-63-1)
Recommended Standards
- (2-((2,6-Dichlorobenzyl)thio)-1-methyl-1H-imidazol-5-yl)methyl (4-nitrophenyl)carbamate (CAS 338422-46-1)
- 1,4,5,8-Tetraamino-2-bromo-7-phenethoxyanthracene-9,10-dione (CAS 88603-43-4)
- (3S,4R,5S)-rel-3-(3-Chloro-2-fluorophenyl)-4-(4-chloro-2-fluorophenyl)-4-cyano-5-neopentylpyrrolidine-2-carboxylic acid (CAS 1219086-89-1)
- 1,4,5,8-Tetraamino-2-bromo-7-(4-ethylphenoxy)anthracene-9,10-dione (CAS 88603-10-5)
- (5-Chloropyridin-3-yl)methanamine dihydrochloride (CAS 1380300-42-4)
- 6-(4-(Ethylthio)phenyl)picolinaldehyde (CAS 887979-61-5)
- N-(4-chlorophenyl)nicotinamide (CAS 14621-03-5)
- Chlorofluoroacetonitrile (CAS 359-05-7)
- 1-(5-Oxaspiro[3.5]Nonan-8-yl)ethan-1-one (CAS 1515737-49-1)
- 2-(4-Pyrazol-1-ylphenyl)acetic acid (CAS 65476-24-6)
- 4-(2-Oxooxazolidin-3-yl)benzenesulfonamide (CAS 444792-24-9)
- 5,5-Dimethyl-4-((4S)-4-methyltetrahydro-2H-pyran-2-yl)-4,5-dihydroisoxazole-3-carboxylic acid (CAS 1910205-48-9)
- 4-(5-Chlorothiophen-2-yl)butan-2-amine (CAS 1094699-95-2)
- (Ser(PO?H?)2?2)-Tau Peptide (260-264) PAb Blocking trifluoroacetate salt (CAS 2022956-57-4)
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