(E)-3-((2-(2-nitro-4-(trifluoromethyl)phenyl)hydrazono)methyl)-1H-indole CAS 339016-00-1

Purity 97%+In StockPharmaceutical Standards
CAS No.339016-00-1
Molecular FormulaC16H11F3N4O2
Molecular Weight348.28 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

(E)-3-((2-(2-nitro-4-(trifluoromethyl)phenyl)hydrazono)methyl)-1H-indole CAS 339016-00-1 chemical structure

Description

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

(E)-3-((2-(2-nitro-4-(trifluoromethyl)phenyl)hydrazono)methyl)-1H-indole (CAS 339016-00-1), molecular formula C16H11F3N4O2 and molecular weight 348.28 g/mol, is a CATO reference standard with documented purity and traceability.

Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution, (E)-3-((2-(2-nitro-4-(trifluoromethyl)phenyl)hydrazono)methyl)-1H-indole is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 348.28 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

As a certified reference material (CRM), (E)-3-((2-(2-nitro-4-(trifluoromethyl)phenyl)hydrazono)methyl)-1H-indole meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC16H11F3N4O2
Molecular Weight348.28 g/mol
AppearancePale yellow to yellow crystalline powder. (slight halide-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)12.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)2025
Halogen ContentF-containing
Nitrogen Atoms4

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