(E)-3-(((4-chlorophenyl)sulfonyl)methyl)-N'-(4-(dimethylamino)benzylidene)-4-nitrobenzohydrazide CAS 339016-43-2
| CAS No. | 339016-43-2 |
| Molecular Formula | C23H21ClN4O5S |
| Molecular Weight | 500.95 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including (E)-3-(((4-chlorophenyl)sulfonyl)methyl)-N'-(4-(dimethylamino)benzylidene)-4-nitrobenzohydrazide.
CATO supplies (E)-3-(((4-chlorophenyl)sulfonyl)methyl)-N'-(4-(dimethylamino)benzylidene)-4-nitrobenzohydrazide (CAS 339016-43-2), a certified reference material (molecular formula C23H21ClN4O5S, MW 500.95 g/mol) for analytical method development and quality control.
(E)-3-(((4-chlorophenyl)sulfonyl)methyl)-N'-(4-(dimethylamino)benzylidene)-4-nitrobenzohydrazide (C23H21ClN4O5S) contains a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), (E)-3-(((4-chlorophenyl)sulfonyl)methyl)-N'-(4-(dimethylamino)benzylidene)-4-nitrobenzohydrazide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C23H21ClN4O5S |
| Molecular Weight | 500.95 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 4 |
| Sulfur Atoms | 1 |
Related E Standards
- 2-((4-(2-Chlorophenyl)-3-cyano-6-phenylpyridin-2-yl)thio)-N-(3-nitrophenyl)acetamide (CAS 332162-77-3)
- 2-((4-(2-Chlorophenyl)-3-cyano-6-phenylpyridin-2-yl)thio)-N-(4-nitrophenyl)acetamide (CAS 332128-34-4)
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- N-(2-(((4-chlorophenyl)sulfonyl)methyl)-4-(pyrrolidine-1-carbonyl)phenyl)-4-fluorobenzamide (CAS 339101-90-5)
- (5-((4-Chlorophenyl)sulfonyl)-1-methyl-3-phenyl-1H-pyrazol-4-yl)methyl 4-chlorobenzoate (CAS 318248-33-8)
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- 3-(4-Chlorophenyl)-2-((2-(4-chlorophenyl)-2-oxoethyl)thio)-5,6,7,8-tetrahydrobenzo[4,5]thieno[2,3-d]pyrimidin-4(3H)-one (CAS 573930-44-6)
Recommended Standards
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- Gastric Inhibitory Polypeptide (6-30) amide (human) (CAS 1139691-72-7)
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