3-Acetyl-N-(5-iodopyridin-2-yl)-5-methylisoxazole-4-carboxamide CAS 339018-07-4
| CAS No. | 339018-07-4 |
| Molecular Formula | C12H10IN3O3 |
| Molecular Weight | 371.13 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies 3-Acetyl-N-(5-iodopyridin-2-yl)-5-methylisoxazole-4-carboxamide (CAS 339018-07-4), a certified reference material (molecular formula C12H10IN3O3, MW 371.13 g/mol) for analytical method development and quality control.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, iodine substitution, 3-Acetyl-N-(5-iodopyridin-2-yl)-5-methylisoxazole-4-carboxamide is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 371.13 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C12H10IN3O3 |
| Molecular Weight | 371.13 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | I-containing |
| Nitrogen Atoms | 3 |
Recommended Standards
- 1,3-Bis(2-chloro-4-nitrophenyl)urea (CAS 96461-96-0)
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- 3-(2,4-Dichloro-5-fluorophenyl)-1-(2,4-difluorophenyl)-1H-pyrazole-4-carbaldehyde (CAS 618101-86-3)
- Tetrahydrothiopyran-4-one (CAS 1072-72-6)
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- 5-Propionyl-6,7-dihydrobenzo[b]thiophen-4(5h)-one (CAS 1341814-32-1)
- 3-[(6-Iodobenzotriazol-1-yl)methyl]thiane 1,1-dioxide (CAS 2287344-11-8)
- TRIS-d11 (crystalline) (CAS 202656-13-1)
- 3-(3-Amino-4-methoxyphenyl)propanoic acid (CAS 859189-60-9)
- Dapagliflozin Impurity 185 (CAS CATO-C4X-1138185)
- 2,3-Difluorobenzoic acid 4519-39-5 AS00860 BENZOIC ACID, 2,3-DIFLUORO- BUTTPARK 45\01-40 RARECHEM AL BO 0251 TIMTEC-BB SBB006679 (CAS 4519-39-5)
- (5-Bromofuran-2-yl)(7,7-dimethyl-6,8-dioxa-2-azaspiro[3.5]nonan-2-yl)methanone (CAS 1396811-36-1)
- Semaglutide impurity 272 (CAS CATO-C4X-2226272)
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