2-{[(4-chlorophenyl)methyl]sulfanyl}-4-(4-methylphenoxy)-5,6,7,8-tetrahydroquinazoline CAS 339019-05-5
| CAS No. | 339019-05-5 |
| Molecular Formula | C22H21ClN2OS |
| Molecular Weight | 396.93 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-{[(4-chlorophenyl)methyl]sulfanyl}-4-(4-methylphenoxy)-5,6,7,8-tetrahydroquinazoline.
CATO supplies 2-{[(4-chlorophenyl)methyl]sulfanyl}-4-(4-methylphenoxy)-5,6,7,8-tetrahydroquinazoline (CAS 339019-05-5), a certified reference material (molecular formula C22H21ClN2OS, MW 396.93 g/mol) for analytical method development and quality control.
The molecular framework of 2-{[(4-chlorophenyl)methyl]sulfanyl}-4-(4-methylphenoxy)-5,6,7,8-tetrahydroquinazoline (C22H21ClN2OS) is characterized by a steroid core, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C22H21ClN2OS |
| Molecular Weight | 396.93 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
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Recommended Standards
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