N-(3,4-Dichlorophenyl)-5-(4-fluorobenzoyl)-1,3-thiazol-2-amine CAS 339022-92-3

Purity 97%+In StockPharmaceutical Standards
CAS No.339022-92-3
Molecular FormulaC16H9Cl2FN2OS
Molecular Weight367.22 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

N-(3,4-Dichlorophenyl)-5-(4-fluorobenzoyl)-1,3-thiazol-2-amine CAS 339022-92-3 chemical structure

Description

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

N-(3,4-Dichlorophenyl)-5-(4-fluorobenzoyl)-1,3-thiazol-2-amine (CAS 339022-92-3) is a high-purity analytical reference standard with the molecular formula C16H9Cl2FN2OS and a molecular weight of 367.22 g/mol.

Structurally, N-(3,4-Dichlorophenyl)-5-(4-fluorobenzoyl)-1,3-thiazol-2-amine (C16H9Cl2FN2OS) contains a nitrogen-containing heterocyclic scaffold, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 12.0, corresponding to approximately 12 ring(s) or double-bond equivalent(s). With a molecular weight of 367.22 g/mol, it falls into the moderately-high-molecular-weight range. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

As a certified reference material (CRM), N-(3,4-Dichlorophenyl)-5-(4-fluorobenzoyl)-1,3-thiazol-2-amine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC16H9Cl2FN2OS
Molecular Weight367.22 g/mol
Purity97%+
StorageStore at 2-8°C, protect from light
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)12.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)2025
Halogen ContentF/Cl-containing
Nitrogen Atoms2
Sulfur Atoms1

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