N-(2,4-difluorophenyl)-6-(isopropylsulfonyl)nicotinamide CAS 339031-21-9
| CAS No. | 339031-21-9 |
| Molecular Formula | C15H14F2N2O3S |
| Molecular Weight | 340.35 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 340.35 g/mol gives N-(2,4-difluorophenyl)-6-(isopropylsulfonyl)nicotinamide distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
N-(2,4-difluorophenyl)-6-(isopropylsulfonyl)nicotinamide (CAS 339031-21-9), molecular formula C15H14F2N2O3S and molecular weight 340.35 g/mol, is a CATO reference standard with documented purity and traceability.
N-(2,4-difluorophenyl)-6-(isopropylsulfonyl)nicotinamide (C15H14F2N2O3S) contains a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C15H14F2N2O3S |
| Molecular Weight | 340.35 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related N Standards
- 1-((5-((3,5-Difluorophenyl)thio)-4-isopropyl-1-methyl-1H-imidazol-2-yl)methyl)urea (CAS 178979-81-2)
- (3,4-Difluorophenyl)(7-(thiophen-2-yl)-1,4-thiazepan-4-yl)methanone (CAS 1705214-86-3)
- 1-(3,4-Difluorophenyl)-N-(2-methylphenyl)-4-oxo-1,4-dihydropyridazine-3-carboxamide (CAS 478063-37-5)
- ((2,6-Difluorophenyl)sulfonyl)phenylalanine (CAS 1242099-15-5)
- N-(2,4-Difluorophenyl)-3,4-dihydro-2H-benzo[b][1,4]dioxepine-7-sulfonamide (CAS 941971-06-8)
- 1-(7-(2,5-Difluorophenyl)-1,4-thiazepan-4-yl)-3,3,3-trifluoropropan-1-one (CAS 1705513-60-5)
- 1-(2,4-Difluorophenyl)-3-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)-1H-pyrazole-4-carbaldehyde (CAS 618101-85-2)
- (2,6-Difluorophenyl)({[2-(morpholin-4-yl)ethyl]carbamoyl})methyl acetate (CAS 866009-28-1)
Recommended Standards
- Methyl 2-{[(1E)-2-{[(ethoxycarbonyl)amino]carbonyl}-3-oxobut-1-en-1-yl]amino}thiophene-3-carboxylate (CAS 338750-48-4)
- N-(4,6-Difluoro-3-propylbenzo[d]thiazol-2(3H)-ylidene)-5,6-dihydro-1,4-dioxine-2-carboxamide (CAS 898349-37-6)
- Ethyl 4-(4-fluorophenyl)-6-hydroxy-2-phenyl-4,5-dihydro-5-pyrimidinecarboxylate (CAS 477867-27-9)
- tert-Butyl 4-(2-fluoro-4-nitrophenoxy)piperidine-1-carboxylate (CAS 250371-88-1)
- 4,5,6,7-Tetrahydroindole (CAS 13618-91-2)
- 1,3-Bis(4-chlorophenyl)-1H-imidazol-3-ium chloride (CAS 141556-46-9)
- 3-(1-Formylcyclopentyl)propanenitrile (CAS 91239-99-5)
- 2,2'-((2-((4-Bromophenyl)amino)-2-oxoethyl)azanediyl)diacetic acid (CAS 5502-60-3)
- 3-methyl-4-phenyl-1,2,5-oxadiazole (CAS 10349-09-4)
- N'-(Piperidine-1-carboximidoyl)piperidine-1-carboximidamide (CAS 1513873-32-9)
- Paraoxon (CAS 311-45-5)
- N-(2-Aminophenyl)-2-Chloronicotinamide (CAS 57841-69-7)
- 4-Bromo-6-isopropylbenzene-1,3-diol (CAS 909870-97-9)
- FMRF-Like Neuropeptide (CAS 121801-61-4)
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