3-[8-Chloro-6-(trifluoromethyl)-[1,2,4]triazolo[4,3-a]pyridin-3-yl]pyridine CAS 339099-70-6
| CAS No. | 339099-70-6 |
| Molecular Formula | C12H6ClF3N4 |
| Molecular Weight | 298.65 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 3-[8-Chloro-6-(trifluoromethyl)-[1,2,4]triazolo[4,3-a]pyridin-3-yl]pyridine is closely related to a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
3-[8-Chloro-6-(trifluoromethyl)-[1,2,4]triazolo[4,3-a]pyridin-3-yl]pyridine (CAS 339099-70-6), molecular formula C12H6ClF3N4 and molecular weight 298.65 g/mol, is a CATO reference standard with documented purity and traceability.
Structurally, 3-[8-Chloro-6-(trifluoromethyl)-[1,2,4]triazolo[4,3-a]pyridin-3-yl]pyridine (C12H6ClF3N4) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 10.0, corresponding to approximately 10 ring(s) or double-bond equivalent(s). With a molecular weight of 298.65 g/mol, it falls into the medium-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 3-[8-Chloro-6-(trifluoromethyl)-[1,2,4]triazolo[4,3-a]pyridin-3-yl]pyridine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H6ClF3N4 |
| Molecular Weight | 298.65 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 4 |
Related Chloro Standards
- 6-Chloro-3-(2-(trifluoromethyl)phenyl)-[1,2,4]triazolo[4,3-b]pyridazine (CAS 1094452-66-0)
- 4-Chloro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazolo[3,4-d]pyrimidine (CAS 1096951-17-5)
- 4-Chloro-1-(4-(trifluoromethyl)phenyl)-1H-pyrazolo[3,4-d]pyrimidine (CAS 1269703-41-4)
- 2-Chloro-4-(morpholin-4-yl)-6-(2,2,2-trifluoroethoxy)-1,3,5-triazine (CAS 1283693-68-4)
- 6-Chloro-3-(4-(trifluoromethyl)phenyl)-[1,2,4]triazolo[4,3-b]pyridazine (CAS 175204-95-2)
- 7-Chloro-2-(3-(trifluoromethyl)phenyl)-2H-pyrazolo[3,4-d]pyridazine (CAS 1956379-80-8)
- 2-[8-Chloro-6-(trifluoromethyl)-[1,2,4]triazolo[4,3-a]pyridin-3-yl]pyridine (CAS 339099-44-4)
- 4-((3-Chloro-5-(trifluoromethyl)pyridin-2-yl)oxy)benzonitrile (CAS 95711-33-4)
Recommended Standards
- 3-(4-Chlorophenoxy)-5-(trifluoromethyl)pyridine-2-carbonitrile (CAS 256658-19-2)
- 6-(2-Chlorophenyl)-2-hydroxy-4-(trifluoromethyl)nicotinonitrile (CAS 338749-70-5)
- 6-(3-Chlorophenyl)-2-hydroxy-4-(trifluoromethyl)nicotinonitrile (CAS 338749-71-6)
- 7-Chloro-5-(3-(trifluoromethyl)phenyl)-[1,2,4]triazolo[1,5-a]pyrimidine (CAS 75175-85-8)
- 4-Chloro-2-(hydroxymethyl)benzimidazole (CAS 1263060-13-4)
- tert-butyl 2,3-dihydropyrrolo[3,2-c]pyridine-1-carboxylate (CAS 219834-81-8)
- 1,8-Dimethyl-1,4,8,11-tetraazacyclotetradecane 1,8-Dimethylcyclam 214078-92-9 (CAS 214078-92-9)
- n-(6-Chloropyridin-2-yl)methanesulfonamide (CAS 1512586-66-1)
- 2-((2-Fluorobenzyl)thio)-6-methyl-5,6,7,8-tetrahydro-1,6-naphthyridine-3-carbonitrile (CAS 496018-73-6)
- Methyl(undecyl)sulfane (CAS 7289-44-3)
- 2-chloro-N-ethylpyridin-4-amine (CAS 931419-00-0)
- 3-((5,8-Dimethoxy-1,4-dioxo-1,4-dihydronaphthalen-2-yl)thio)propanoic acid (CAS 1227401-27-5)
- 4-Bromo-6-chloropicolinamide (CAS 1807072-80-5)
- Des-Leu14-Tirzepatide (CAS CATO-CPTD788959)
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